Hypokalemia during antibiotic treatment for bone and joint infections

Hypokalemia during antibiotic treatment for bone and joint infections Eur J Orthop Surg Traumatol (2018) 28:389–395 https://doi.org/10.1007/s00590-017-2054-1 ORIGINAL ARTICLE • GENERAL ORTHOPAEDICS - INFECTION Hypokalemia during antibiotic treatment for bone and joint infections 1 2 1 Carmen Falcone  · Leonida Compostella  · Antonella Camardo  · 2 1 Li Van Stella Truong  · Francesco Centofanti   Received: 4 July 2017 / Accepted: 8 October 2017 / Published online: 10 October 2017 © Springer-Verlag France SAS 2017 Abstract Conclusions Appearance of severe hypokalemia is a fre- Purpose During treatment of bone and joint infections quent event among patients treated for BJIs with multiple (BJIs) with multiple antibiotic therapy, hypokalemia has antibiotic therapy, when this is prescribed in older age been reported as a rare side effect. The aim of this study patients and associated with simultaneous use of diuretics. was to evaluate incidence and risk factors for hypokalemia Due to possible increase in mortality risk in the short term, in a cohort of patients treated with multidrug therapy for particular caution should be paid during intensive antibiotic BJIs, in a single center. treatment in these groups of patients. Methods We retrospectively reviewed 331 clinical files of 150 consecutive patients (65% males; median age 59 years, Keywords Osteomyelitis · Joint infections · 95% CI 55–62) admitted repeatedly to our Osteomyelitis Spondylodiscitis · Antibiotics · Hypokalemia · Diuretic · http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Orthopaedic Surgery & Traumatology Springer Journals

Hypokalemia during antibiotic treatment for bone and joint infections

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer-Verlag France SAS
Subject
Medicine & Public Health; Surgical Orthopedics; Traumatic Surgery
ISSN
1633-8065
eISSN
1432-1068
D.O.I.
10.1007/s00590-017-2054-1
Publisher site
See Article on Publisher Site

Abstract

Eur J Orthop Surg Traumatol (2018) 28:389–395 https://doi.org/10.1007/s00590-017-2054-1 ORIGINAL ARTICLE • GENERAL ORTHOPAEDICS - INFECTION Hypokalemia during antibiotic treatment for bone and joint infections 1 2 1 Carmen Falcone  · Leonida Compostella  · Antonella Camardo  · 2 1 Li Van Stella Truong  · Francesco Centofanti   Received: 4 July 2017 / Accepted: 8 October 2017 / Published online: 10 October 2017 © Springer-Verlag France SAS 2017 Abstract Conclusions Appearance of severe hypokalemia is a fre- Purpose During treatment of bone and joint infections quent event among patients treated for BJIs with multiple (BJIs) with multiple antibiotic therapy, hypokalemia has antibiotic therapy, when this is prescribed in older age been reported as a rare side effect. The aim of this study patients and associated with simultaneous use of diuretics. was to evaluate incidence and risk factors for hypokalemia Due to possible increase in mortality risk in the short term, in a cohort of patients treated with multidrug therapy for particular caution should be paid during intensive antibiotic BJIs, in a single center. treatment in these groups of patients. Methods We retrospectively reviewed 331 clinical files of 150 consecutive patients (65% males; median age 59 years, Keywords Osteomyelitis · Joint infections · 95% CI 55–62) admitted repeatedly to our Osteomyelitis Spondylodiscitis · Antibiotics · Hypokalemia · Diuretic ·

Journal

European Journal of Orthopaedic Surgery & TraumatologySpringer Journals

Published: Oct 10, 2017

References

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