Int Ophthalmol (2018) 38:1347–1350 https://doi.org/10.1007/s10792-017-0573-8 CASE REPORT Human papillomavirus (HPV)-associated trilateral squamous neoplasia in immunocompetent individual . . . . Alfonso Iovieno Simonetta Piana Laura Chiesi Cristina Fodero Luigi Fontana Received: 11 December 2016 / Accepted: 20 May 2017 / Published online: 6 June 2017 Springer Science+Business Media Dordrecht 2017 Abstract repeated exposure to HPV could explain coexistence Purpose To describe a case of bilateral conjunctival of different genotypes. and cervical human papillomavirus (HPV)-related squamous neoplasia. Keywords OSSN HPV Conjunctiva Neoplasia Case description A healthy immunocompetent 55-year-old lady came to our attention for prosecution of care of a right recurrent conjunctival squamous cell carcinoma. Upon examination, she was found disease- Introduction free in the right eye but displayed a left conjunctival intraepithelial neoplasia (CIN grade I) and low-grade Ocular surface squamous neoplasia (OSSN) is among cervical squamous dysplasia. HPV infection with the most common neoplasms of the conjunctiva . genotypes 16 (right eye), 11 and 39 (left eye) and 39 OSSN is unilateral in the majority of cases . Risk (uterine cervix) was also detected. factors for the development of OSSN include sun Conclusion Simultaneous uterine and conjunctival exposure and human immunodeﬁciency virus (HIV) HPV-related squamous
International Ophthalmology – Springer Journals
Published: Jun 6, 2017
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