Human circulating and tissue gastric cancer stem cells display distinct epithelial–mesenchymal features and behaviors

Human circulating and tissue gastric cancer stem cells display distinct epithelial–mesenchymal... J Cancer Res Clin Oncol (2017) 143:1687–1699 DOI 10.1007/s00432-017-2417-3 ORIGINAL ARTICLE – CANCER RESEARCH Human circulating and tissue gastric cancer stem cells display distinct epithelial–mesenchymal features and behaviors 1 1 2 1 1 Shengliang Zhang · Yanna Shang · Tie Chen · Xin Zhou · Wengtong Meng · 3 1 1 1 1 Chuanwen Fan · Ran Lu · Qiaorong Huang · Xue Li · Xu Hong · 3 4 1 Zongguang Zhou · Jiankun Hu · Xianming Mo Received: 4 November 2016 / Accepted: 31 March 2017 / Published online: 20 April 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract human gastric adenocarcinoma. The CGCSCs and TGC- Introduction Metastasis is a leading cause of cancer- SCs were culture in a same serum free stem cell culture related-deaths worldwide. Recently, cancer stem cells medium, however the morphology are different with each (CSCs) have been believed to be responsible for tumor other. EMT-associated markers were measured by Immu- initiation and metastasis, but till now, difference of cellu- nofluorescence, Western Blotting, and RT-PCR methods, lar features and behaviors between CSCs from tumor tis- and the results indicated that the CGCSCs and TGCSCs sues (TCSCs) and circulation (CCSCs) remains largely carry different epithelial–mesenchymal http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Cancer Research and Clinical Oncology Springer Journals

Human circulating and tissue gastric cancer stem cells display distinct epithelial–mesenchymal features and behaviors

Loading next page...
 
/lp/springer_journal/human-circulating-and-tissue-gastric-cancer-stem-cells-display-XkD8dP0dNL
Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Oncology; Cancer Research; Internal Medicine; Hematology
ISSN
0171-5216
eISSN
1432-1335
D.O.I.
10.1007/s00432-017-2417-3
Publisher site
See Article on Publisher Site

Abstract

J Cancer Res Clin Oncol (2017) 143:1687–1699 DOI 10.1007/s00432-017-2417-3 ORIGINAL ARTICLE – CANCER RESEARCH Human circulating and tissue gastric cancer stem cells display distinct epithelial–mesenchymal features and behaviors 1 1 2 1 1 Shengliang Zhang · Yanna Shang · Tie Chen · Xin Zhou · Wengtong Meng · 3 1 1 1 1 Chuanwen Fan · Ran Lu · Qiaorong Huang · Xue Li · Xu Hong · 3 4 1 Zongguang Zhou · Jiankun Hu · Xianming Mo Received: 4 November 2016 / Accepted: 31 March 2017 / Published online: 20 April 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract human gastric adenocarcinoma. The CGCSCs and TGC- Introduction Metastasis is a leading cause of cancer- SCs were culture in a same serum free stem cell culture related-deaths worldwide. Recently, cancer stem cells medium, however the morphology are different with each (CSCs) have been believed to be responsible for tumor other. EMT-associated markers were measured by Immu- initiation and metastasis, but till now, difference of cellu- nofluorescence, Western Blotting, and RT-PCR methods, lar features and behaviors between CSCs from tumor tis- and the results indicated that the CGCSCs and TGCSCs sues (TCSCs) and circulation (CCSCs) remains largely carry different epithelial–mesenchymal

Journal

Journal of Cancer Research and Clinical OncologySpringer Journals

Published: Apr 20, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off