HIV-1 particles have been studied by structural and chemical approaches, however, the processes of assembly, budding and maturation are just beginning to be characterized, and molecular details of these processes remain poorly defined. This brief review summarizes some recent findings on the final steps of the HIV-1 life cycle and touches upon some unanswered questions, particularly regarding the processes involved in virus maturation and infectivity.
Archives of Virology – Springer Journals
Published: Jun 1, 2004
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