Monatsh Chem (2017) 148:1613–1618 DOI 10.1007/s00706-017-1940-x ORIGINAL PAPER 1 1 2 1 3 • • • • Karel Kudla ´ c ˇek Karel Nesme ˇra ´ k Martin Stı ´cha Petr Kozlı ´k Jan Babica Received: 26 January 2017 / Accepted: 13 February 2017 / Published online: 30 June 2017 Springer-Verlag Wien 2017 Abstract Two injection solutions of quinine 79, 77 resp., Introduction years were analyzed using RP-HPLC. The conditions of separation were optimized. The quinine content is A study of historical pharmaceutical relicts is an interesting decreased about 13% for 79-year-old sample and about 8% part of archaeological chemistry [1, 2], as it helps reveal for 77-year-old sample, respectively. Quinotoxine has been the composition, purpose, and/or chemical changes of found as the decomposition product. The compounds were analyzed object in pharmaceutical as well as historical identiﬁed by MS , and the ESI fragmentation mechanisms context. Nevertheless, the analysis of mass produced of compounds found were proposed. medicinal products which are produced since the second Graphical abstract half of the 19th century are relatively rare yet. Only the following analyses have been published: a series of so- called patent medicines from the 19th century [3, 4], injection solution of
Monatshefte für Chemie - Chemical Monthly – Springer Journals
Published: Jun 30, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera