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Histiocytic Necrotizing Lymphadenitis Involving the Neck: Radiology-Pathology Correlation

Histiocytic Necrotizing Lymphadenitis Involving the Neck: Radiology-Pathology Correlation Histiocytic necrotizing lymphadenitis is an uncommon autoimmune condition characterized by fever, leukopenia, and neck swelling. Diagnostic imaging, including ultrasound and CT, typically demonstrates conglomerates of enlarged cervical lymph nodes with hypervascular cortices and areas of necrosis. Ultimately, the diagnosis is confirmed with the histopathologic findings of paracortical coagulative necrosis with karyorrhectic debris, abundant histiocytes, and absence of neutrophils. Other potential etiologies, such as other causes of infectious lymphadenitis, tuberculosis, lymphoma, and systemic lupus erythematosus, must be excluded. These features are exemplified in this sine qua non radiology–pathology correlation article. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Head and Neck Pathology Springer Journals

Histiocytic Necrotizing Lymphadenitis Involving the Neck: Radiology-Pathology Correlation

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Publisher
Springer Journals
Copyright
Copyright © Springer Science+Business Media, LLC, part of Springer Nature 2018
Subject
Medicine & Public Health; Pathology; Otorhinolaryngology; Oral and Maxillofacial Surgery; Dentistry
eISSN
1936-0568
DOI
10.1007/s12105-018-0936-0
Publisher site
See Article on Publisher Site

Abstract

Histiocytic necrotizing lymphadenitis is an uncommon autoimmune condition characterized by fever, leukopenia, and neck swelling. Diagnostic imaging, including ultrasound and CT, typically demonstrates conglomerates of enlarged cervical lymph nodes with hypervascular cortices and areas of necrosis. Ultimately, the diagnosis is confirmed with the histopathologic findings of paracortical coagulative necrosis with karyorrhectic debris, abundant histiocytes, and absence of neutrophils. Other potential etiologies, such as other causes of infectious lymphadenitis, tuberculosis, lymphoma, and systemic lupus erythematosus, must be excluded. These features are exemplified in this sine qua non radiology–pathology correlation article.

Journal

Head and Neck Pathology – Springer Journals

Published: Dec 1, 2019

Keywords: Histiocytic necrotizing lymphadenitis; Neck; Lymph node; Radiology; Pathology

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