High-resolution mapping of the spm (niemann-pick type C) locus on mouse chromosome 18

High-resolution mapping of the spm (niemann-pick type C) locus on mouse chromosome 18 Mammalian Genome 8, 355-356 (1997). 9 Spnnger-Verlag New York Inc 1997 High-resolution mapping of the spm (Niemann-Pick Type C) locus on mouse Chromosome 18 R.P. Erickson, 1'2 R.A. Aviles, 1 J. Zhang, l'a M.A. Kozloski, 1 W.S. Garver, l R.A. Heidenreich 1'4 IAngel Charity for Children-Wings for Genetic Research, Steele Memorial Children's Research Center, Department of Pediatrics, University of Arizona, Tucson, Arizona 85724, USA 2Department of Molecular and Cellular Biology, Umversity of Arizona, Tucson, Arizona 85724, USA 3Genetics Committee, University of Arizona, Tucson, Arizona 85724, USA 4Department of Biochemistry, University of Arizona, Tucson, Arizona 85724, USA Received: 13 September 1996 / Accepted: 13 December 1996 In the early 1980' s, reports of two independent mutations causing affected mice, at 21.4% for which both parents were carders, is a new storage disease with neurological manifestations, which are significant and is in line with previous results; Morris et al. 1982) now known to represent the murine equivalent of Niemann-Pick and 8 mice from a noncarrier F 1 (for a total of 948). We also found Type C, appeared (Pentchev et al. 1980; Miyawaki et al. 1982). moderate sex differences in recombination frequencies; therefore, The latter publication recognized the relationship to Niemann-Pick http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

High-resolution mapping of the spm (niemann-pick type C) locus on mouse chromosome 18

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Publisher
Springer-Verlag
Copyright
Copyright © 1997 by Springer-Verlag
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900440
Publisher site
See Article on Publisher Site

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