Mammalian Genome 8, 355-356 (1997). 9 Spnnger-Verlag New York Inc 1997 High-resolution mapping of the spm (Niemann-Pick Type C) locus on mouse Chromosome 18 R.P. Erickson, 1'2 R.A. Aviles, 1 J. Zhang, l'a M.A. Kozloski, 1 W.S. Garver, l R.A. Heidenreich 1'4 IAngel Charity for Children-Wings for Genetic Research, Steele Memorial Children's Research Center, Department of Pediatrics, University of Arizona, Tucson, Arizona 85724, USA 2Department of Molecular and Cellular Biology, Umversity of Arizona, Tucson, Arizona 85724, USA 3Genetics Committee, University of Arizona, Tucson, Arizona 85724, USA 4Department of Biochemistry, University of Arizona, Tucson, Arizona 85724, USA Received: 13 September 1996 / Accepted: 13 December 1996 In the early 1980' s, reports of two independent mutations causing affected mice, at 21.4% for which both parents were carders, is a new storage disease with neurological manifestations, which are significant and is in line with previous results; Morris et al. 1982) now known to represent the murine equivalent of Niemann-Pick and 8 mice from a noncarrier F 1 (for a total of 948). We also found Type C, appeared (Pentchev et al. 1980; Miyawaki et al. 1982). moderate sex differences in recombination frequencies; therefore, The latter publication recognized the relationship to Niemann-Pick
Mammalian Genome – Springer Journals
Published: Mar 21, 2009
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