Hiccups in Parkinson’s disease: an analysis of cases reported in the European pharmacovigilance database and a review of the literature

Hiccups in Parkinson’s disease: an analysis of cases reported in the European pharmacovigilance... Eur J Clin Pharmacol (2017) 73:1159–1164 DOI 10.1007/s00228-017-2275-6 PHARMACOEPIDEMIOLOGY AND PRESCRIPTION Hiccups in Parkinson’s disease: an analysis of cases reported in the European pharmacovigilance database and a review of the literature 1 2 3 2 2 U. Lertxundi & A.C Marquínez & S. Domingo-Echaburu & M.Á Solinís & B. Calvo & 2 4 4 2 A. Del Pozo-Rodríguez & M. García & C. Aguirre & A. Isla Received: 31 January 2017 /Accepted: 26 May 2017 /Published online: 9 June 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract disease, dopamine agonists, and hiccups, searching for specif- Background Some reports have suggested an association be- ic treatment recommendations for hiccups in this disease. tween dopamine agonists and hiccups, involuntary contrac- Results Both rotigotine and pramipexole fulfilled the criteria to tions that merit full clinical attention because they can be very generate a safety signal. We found 32 and 13 cases of hiccups debilitating. Many drugs frequently used to treat hiccups are associated with dopamine agonists in EudraVigilance and the formally contraindicated in Parkinson’s disease due to their literature, respectively. There were no specific recommenda- liability to worsen motor symptoms, making the treatment of tions for the management of hiccups in Parkinson’s disease in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Clinical Pharmacology Springer Journals

Hiccups in Parkinson’s disease: an analysis of cases reported in the European pharmacovigilance database and a review of the literature

Loading next page...
 
/lp/springer_journal/hiccups-in-parkinson-s-disease-an-analysis-of-cases-reported-in-the-iQ0AOGK0zI
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Biomedicine; Pharmacology/Toxicology
ISSN
0031-6970
eISSN
1432-1041
D.O.I.
10.1007/s00228-017-2275-6
Publisher site
See Article on Publisher Site

Abstract

Eur J Clin Pharmacol (2017) 73:1159–1164 DOI 10.1007/s00228-017-2275-6 PHARMACOEPIDEMIOLOGY AND PRESCRIPTION Hiccups in Parkinson’s disease: an analysis of cases reported in the European pharmacovigilance database and a review of the literature 1 2 3 2 2 U. Lertxundi & A.C Marquínez & S. Domingo-Echaburu & M.Á Solinís & B. Calvo & 2 4 4 2 A. Del Pozo-Rodríguez & M. García & C. Aguirre & A. Isla Received: 31 January 2017 /Accepted: 26 May 2017 /Published online: 9 June 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract disease, dopamine agonists, and hiccups, searching for specif- Background Some reports have suggested an association be- ic treatment recommendations for hiccups in this disease. tween dopamine agonists and hiccups, involuntary contrac- Results Both rotigotine and pramipexole fulfilled the criteria to tions that merit full clinical attention because they can be very generate a safety signal. We found 32 and 13 cases of hiccups debilitating. Many drugs frequently used to treat hiccups are associated with dopamine agonists in EudraVigilance and the formally contraindicated in Parkinson’s disease due to their literature, respectively. There were no specific recommenda- liability to worsen motor symptoms, making the treatment of tions for the management of hiccups in Parkinson’s disease in

Journal

European Journal of Clinical PharmacologySpringer Journals

Published: Jun 9, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off