Heparin

Heparin Reactions 1680, p156 - 2 Dec 2017 Thrombocytopenia: case report A 65-year-old woman developed thrombocytopenia during treatment with heparin. The woman, who was diagnosed with multilevel – – spondylosis and adjacent level breakdown at C4 5 and C6 7, – – underwent revision fusions of C4 5 and C6 7 levels. On the post-operative day 2, she developed ipsilateral carotid thrombosis. Subsequently, she underwent exploration and thrombectomy of the left carotid artery. During the thrombectomy, clamping was performed. Prior to the clamping, she received heparin injection [dosage and route not stated]. Following the release of all vascular clamps and after obtaining good pulsations in the carotid arteries, the injected heparin was reversed with protamine sulfate, and haemostasis was achieved. Consequently, she developed heparin-induced thrombocytopenia [time to reaction onset not stated]. The woman’s hospital stay was prolonged due to the thrombocytopenia. On the postoperative day 20, she was discharged without any residual deficits. At 9-month follow- up, she was asymptomatic and fully functional. Author comment: "Our patient’s hospital stay was further complicated by . . . a heparin-induced thrombocytopenia." Chin KR, et al. Postoperative cervical haematoma complicated by ipsilateral carotid thrombosis and aphasia after anterior cervical fusion: A case report. Case Reports in Medicine 2013: 2013. Available from: URL: http:// doi.org/10.1155/2013/590639 - USA 803284056 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Heparin

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-017-39087-3
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p156 - 2 Dec 2017 Thrombocytopenia: case report A 65-year-old woman developed thrombocytopenia during treatment with heparin. The woman, who was diagnosed with multilevel – – spondylosis and adjacent level breakdown at C4 5 and C6 7, – – underwent revision fusions of C4 5 and C6 7 levels. On the post-operative day 2, she developed ipsilateral carotid thrombosis. Subsequently, she underwent exploration and thrombectomy of the left carotid artery. During the thrombectomy, clamping was performed. Prior to the clamping, she received heparin injection [dosage and route not stated]. Following the release of all vascular clamps and after obtaining good pulsations in the carotid arteries, the injected heparin was reversed with protamine sulfate, and haemostasis was achieved. Consequently, she developed heparin-induced thrombocytopenia [time to reaction onset not stated]. The woman’s hospital stay was prolonged due to the thrombocytopenia. On the postoperative day 20, she was discharged without any residual deficits. At 9-month follow- up, she was asymptomatic and fully functional. Author comment: "Our patient’s hospital stay was further complicated by . . . a heparin-induced thrombocytopenia." Chin KR, et al. Postoperative cervical haematoma complicated by ipsilateral carotid thrombosis and aphasia after anterior cervical fusion: A case report. Case Reports in Medicine 2013: 2013. Available from: URL: http:// doi.org/10.1155/2013/590639 - USA 803284056 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

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