Hemophagocytic lymphohistiocytosis (HLH) secondary to Ehrlichia chaffeensis with bone marrow involvement

Hemophagocytic lymphohistiocytosis (HLH) secondary to Ehrlichia chaffeensis with bone marrow... Ann Hematol (2017) 96:1755–1758 DOI 10.1007/s00277-017-3085-8 LETTER TO THE EDITOR Hemophagocytic lymphohistiocytosis (HLH) secondary to Ehrlichia chaffeensis with bone marrow involvement 1 1 2 3 Abdul Rafeh Naqash & Meera Yogarajah & Bethany Dawn Vallangeon & Maida Hafiz & 3 4 5 1 Deval Patel & Evelina Kolychev & Dora Alexandra Lebron & Darla Liles Received: 21 July 2017 /Accepted: 24 July 2017 /Published online: 31 July 2017 Springer-Verlag GmbH Germany 2017 Dear Editor, A 66-year-old African American female with a history of Hemophagocytic lymphohistiocytosis (HLH) is a rare life- HIV and noncompliance with anti-retroviral medications pre- threatening clinical syndrome of hyper inflammation that sented with septic shock requiring vasopressors. On admis- leads to a dysregulated and ineffective immune activation sion, the temperature was 38.2 °C; heart rate was in the 140 s; [1]. Patients can often present similar to a sepsis-like syn- examination was remarkable for lethargy and diffuse abdom- drome with multi-organ dysfunction, and despite treat- inal pain. A computed tomography scan of the abdomen/ ment, a high mortality rate is observed [2]. HLH is clas- pelvis was unrevealing. Complete blood count was notable sified as primary or familial when a gene mutation is for pancytopenia with http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Hematology Springer Journals

Hemophagocytic lymphohistiocytosis (HLH) secondary to Ehrlichia chaffeensis with bone marrow involvement

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Springer Berlin Heidelberg
Copyright © 2017 by Springer-Verlag GmbH Germany
Medicine & Public Health; Hematology; Oncology
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