Access the full text.
Sign up today, get DeepDyve free for 14 days.
JS Belle, M. Heisenberg (1994)
Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodies.Science, 263 5147
Savvateeva Ev, Popov Av, N. Kamyshev, Bragina Jv, M. Heisenberg, D. Senitz, J. Kornhuber, P. Riederer (2000)
Age-dependent memory loss, synaptic pathology and altered brain plasticity in the Drosophila mutant cardinal accumulating 3-hydroxykynurenineJournal of Neural Transmission, 107
D. Smith, L. Whitesell, Emmanuel Katsanis (1998)
Molecular chaperones: biology and prospects for pharmacological intervention.Pharmacological reviews, 50 4
(1999)
Drosophila melanogaster mRNA for Tip Associating Protein (sbr Gene)
M. Evgen’ev, A. Levin, E. Lozovskaya (1979)
The analysis of a temperature-sensitive (ts) mutation influencing the expression of heat shock-inducible genes in Drosophila melanogasterMolecular and General Genetics MGG, 176
I. Yahara (1992)
[Stress response and stress proteins].Seikagaku. The Journal of Japanese Biochemical Society, 64 10
M. Feder, D. Parsell, S. Lindquist (1995)
Cell Biology of Trauma
Isabelle Braun, E. Rohrbach, C. Schmitt, E. Izaurralde (1999)
TAP binds to the constitutive transport element (CTE) through a novel RNA‐binding motif that is sufficient to promote CTE‐dependent RNA export from the nucleusThe EMBO Journal, 18
D. Yoon, H. Lee, W. Seol, M. Demaria, M. Rosenzweig, J. Jung (1997)
Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation.Immunity, 6 5
B. Lankat-Buttgereit, R. Tampé (1999)
The transporter associated with antigen processing TAP: structure and functionFEBS Letters, 464
(1999)
Detection of Drosophila Mutants Displaying Memory Defects after Conditioned Courtship Suppression
(1982)
Report of New Mutants, Dros
A. Segref, K. Sharma, V. Doye, A. Hellwig, J. Huber, R. Lührmann, E. Hurt (1997)
Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear poresThe EMBO Journal, 16
M. Heisenberg (1994)
Neural Basis of Behavioral Adaptations
(1980)
The Effect of a ts Mutation on the Expression of Heat Shock-Inducible Genes in Drosophila melanogaster: 1. Analysis of Protein Synthesis
E. Nigg (1997)
Nucleocytoplasmic transport: signals, mechanisms and regulationNature, 386
W. Welch (1991)
The role of heat-shock proteins as molecular chaperones.Current opinion in cell biology, 3 6
D. Parsell, S. Lindquist (1993)
The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins.Annual review of genetics, 27
Ronald Davis (1996)
Physiology and biochemistry of Drosophila learning mutants.Physiological reviews, 76 2
L.A. Mamon, E.A. Nikitina, O.M. Pugacheva, E.V. Golubkova (1999)
The Effects of the Maternal and Paternal Organisms on Thermosensitivity Determined by the l(1)ts403 Mutation in Drosophila melanogaster Early EmbryosGenetika, 35
(1993)
The Role of HeatShock Proteins in Repair of Mitotic Chromosome Damage Induced by a High Temperature in D. melanogaster
N.A. Ranson, H.E. White, H.R. Saibil (1998)
ChaperoninsBiochem. J., 333
(1979)
The Analysis of Temperature - Sensitive ( ts ) Mutation Influencing the Expression of Heat ShockInducible Genes in D . melanogaster
Andrew Smith (1998)
Genome sequence of the nematode C-elegans: A platform for investigating biologyScience, 282
(1998)
Development of Thermotolerance in Drosophila melanogaster Strain l(1)ts403 with Distorted Synthesis of Heat-Shock Proteins
R.R. Sokal, F.J. Rohlf (1995)
Biometry
L. Mamon, E. Mazur, I. Churkina, L. Barabanova (1990)
[The effect of high temperature on the frequency of nondisjunction and loss of sex chromosomes in females of Drosophila melanogaster strain I(1)ts403 with a defect in the heat shock protein system].Genetika, 26 3
(1980)
The Effect of a ts Mutation on the Expression of Heat ShockInducible Genes in Drosophila melanogaster : 1
Isabelle Boquet, R. Hitier, Michèle Dumas, Michel Chaminade, Thomas Preat (2000)
Central brain postembryonic development in Drosophila: implication of genes expressed at the interhemispheric junction.Journal of neurobiology, 42 1
I.F. Zhimulev, E.S. Belyaeva, G.V. Pokholkova (1982)
Report of New MutantsDros. Inf. Serv., 58
(1993)
The Role of HeatShock Proteins in Restoration of Cell Proliferation after Exposure of D. melanogaster Larvae to a High Temperature
(1994)
Central Brain Function in Insects: Genetic Studies on the Mushroom Bodies and Central Complex in Drosophila
(1999)
Consequences of Cell Stress in Drosophila with Altered Synthesis of Heat-Shock Proteins, Vestn
L.A. Mamon, E.L. Mazur, I.V. Churkina, L.V. Barabanova (1990)
The Effect of High Temperatures on the Nondisjunction Frequency and Loss of the Sex Chromosomes in Females of Drosophila melanogaster Strain l(1)ts403 Defective in the System of Heat-Shock ProteinsGenetika, 26
M. La, Kutskova IuA (1993)
[Role of heat-shock proteins in recovery of cell proliferation following high temperature treatment of Drosophila melanogaster larvae]., 29
L. Mamon, E. Nikitina, O. Pugacheva, E. Golubkova (1999)
[Maternal and paternal effects on the specific mutation l(1)ts403 of thermosensitivity of early Drosophila melanogaster embryos].Genetika, 35 8
(1999)
The Influence of the l(1)ts403 Allele on the Heat Induction of the Different Malformations in Drosophila melanogaster, 40th Ann
L. Mamon, A. Komarova, L. Bondarenko, L. Barabanova, M. Tikhomirova (1998)
[Development of thermotolerance in Drosophila melanogaster line l(1) ts403 with a defect in heat shock protein synthesis].Genetika, 34 7
(1999)
Detection of Drosophila Mutants Displaying Memory Defects after Conditioned Courtship Suppression, Fiziol
R. Arking (1975)
Temperature-sensitive cell-lethal mutants of drosophila: isolation and characterization.Genetics, 3
Martin Heisenberg, Alexander Borst, Sibylle Wagner, Duncan Byers (1985)
Drosophila mushroom body mutants are deficient in olfactory learning.Journal of neurogenetics, 2 1
N. Kamyshev, K. Iliadi, J. Bragina (1999)
Drosophila conditioned courtship: two ways of testing memory.Learning & memory, 6 1
(1995)
Stress Response and Stress Proteins, Cell Biology of Trauma
The structures and functions of many genes are homologous in Drosophilaand humans. Therefore, studying pathological processes in Drosophila, in particular neurogenerative processes accompanied by progressive memory loss, helps to understand the ethiology of corresponding human disorders and to develop therapeutic strategies. It is believed that the development of neurogenerative diseases might result from alterations in the functioning of the heat shock/chaperone machinery. In view of this, we used Drosophila mutant l(1)ts403 with defective synthesis of heat shock proteins for studying learning and memory in a test of conditioned courtship suppression following a heat shock given at different developmental stages. High learning indices were registered immediately and 30 min after training both in the intact controls and in flies subjected to different developmental heat shocks. This indicated normal learning and memory acquisition in the mutant. At the same time, memory retention (3 h after training) suffered to different extent depending on the developmental stage. The remote effects of heat shock given during the formation of the mushroom bodies indicated the important role of this brain structure in the memory formation. The observed memory defects may result from alterations both in mRNA transport and in the functions of molecular chaperones in the l(1)ts403 mutant.
Russian Journal of Genetics – Springer Journals
Published: Oct 7, 2004
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.