Growth and development peculiarities of testicles in postpubertal period in inbred mice lines PT and CBA/Lac

Growth and development peculiarities of testicles in postpubertal period in inbred mice lines PT... The goal of this study is to perform a comparative genetic investigation of testicle development during the postpubescence period (from days 70 to 90 of life) in the inbred mice lines PT and CBA/Lac. Interlinear differences in the body and testicular weight, serum testosterone concentration, number of epididymal spermatozoa, area of testicular epithelium, semeniferous tubule lumen, and insulae of Leydig cells were analyzed. It was found that the morphological and histomorphometric parameters of testicles in males from the PT line compared to the males of the CBA/Lac line did not reach a definitive stage with the end of the post-pubescence period and kept on developing until day 90 of life. Therefore, genetic differences remain in the postpubertal testicular development of laboratory mice. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Developmental Biology Springer Journals

Growth and development peculiarities of testicles in postpubertal period in inbred mice lines PT and CBA/Lac

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Publisher
SP MAIK Nauka/Interperiodica
Copyright
Copyright © 2012 by Pleiades Publishing, Ltd.
Subject
Life Sciences; Animal Anatomy / Morphology / Histology; Developmental Biology
ISSN
1062-3604
eISSN
1608-3326
D.O.I.
10.1134/S1062360412050049
Publisher site
See Article on Publisher Site

Abstract

The goal of this study is to perform a comparative genetic investigation of testicle development during the postpubescence period (from days 70 to 90 of life) in the inbred mice lines PT and CBA/Lac. Interlinear differences in the body and testicular weight, serum testosterone concentration, number of epididymal spermatozoa, area of testicular epithelium, semeniferous tubule lumen, and insulae of Leydig cells were analyzed. It was found that the morphological and histomorphometric parameters of testicles in males from the PT line compared to the males of the CBA/Lac line did not reach a definitive stage with the end of the post-pubescence period and kept on developing until day 90 of life. Therefore, genetic differences remain in the postpubertal testicular development of laboratory mice.

Journal

Russian Journal of Developmental BiologySpringer Journals

Published: Sep 16, 2012

References

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