2,4,5-Trisubstituted pyrrole derivatives were efficiently synthesized by one-pot condensation of 1,3-diones, α-bromoacetophenones, and ammonium acetate in ionic liquid [bmim]BF4. The new synthetic method offers multisubstituted pyrroles with the advantages of mild reaction conditions, operational simplicity, higher yield, and environmental friendliness.
Research on Chemical Intermediates – Springer Journals
Published: Mar 9, 2016
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