Glycerol assisted eco-friendly strategy for the facile
synthesis of 4,4
pyrazol-5-ols) and 2-aryl-2,3-dihydroquinazolin-
4(1H)-ones under catalyst-free conditions
Received: 27 June 2016 / Accepted: 1 September 2016 / Published online: 16 September 2016
Ó Springer Science+Business Media Dordrecht 2016
This article describes glycerol mediated eco-friendly approaches for the
convenient access of structurally diverse 4,4
5-ol) and 2-aryl-2,3-dihydroquinazolin-4(1H)-one motifs under catalyst-free conditions.
Prominent advantages include clean processes, atom-efﬁciency, simplicity of the work-
up, neutral conditions, low-cost reaction medium, excellent product yield and solvent
reusability, in addition to relatively shorter reaction times.
Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2728-z)
contains supplementary material, which is available to authorized users.
& Appaswami Lalitha
Synthetic Organic Chemistry Research Laboratory, Department of Chemistry, Periyar
University, Periyar Palkalai Nagar, Salem, Tamil Nadu 636011, India
Department of Chemistry, Salem Sowdeswari College, Salem, Tamil Nadu 636010, India
Res Chem Intermed (2017) 43:1767–1782