ISSN 1022-7954, Russian Journal of Genetics, 2008, Vol. 44, No. 2, pp. 244–245. © Pleiades Publishing, Inc., 2008. Original Russian Text © the Editorial Board, 2008, published in Genetika, 2008, Vol. 44, No. 2, pp. 287–288. CHRONICLE Georgy Pavlovich Georgiev: To the 75th Anniversary DOI: 10.1134/S1022795408020191 In no way providing a complete description, we would like to note the following most essential achieve- ments of Georgiev that determined the development of several independent directions in molecular biology and molecular genetics. 1960: Using electron microscopy, it was for the ﬁrst time demonstrated that eukaryotic cells contain a nuclear skeleton (nuclear matrix) to which DNA is attached; as has been shown later, this DNA corre- sponds to replicons. 1961: Discovery of high-molecular-weight nuclear precursors of messenger RNA (pre-mRNA and DNA- like RNA) and development of the concept of pre- mRNA conversion into mature cytoplasmic mRNA, during which the main part of pre-mRNA fragments in the nucleus degrade. 1965: Discovery of nuclear ribonucleoprotein (RNP) particles and determination of their native struc- ture (1968); their organization pattern appeared com- mon for other structures, in particular, nucleosomes. 1976–1977: Discovery of various classes of mobile genetic elements in animals, such as drosophila MDG Georgy Pavlovich
Russian Journal of Genetics – Springer Journals
Published: Mar 25, 2011
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