Gentamicin Reactions 1680, p154 - 2 Dec 2017 Ototoxicity: case report A 50-year-old man developed ototoxicity during treatment with gentamicin [gentamycin]. The man, who had a history of hypertension and diabetes, underwent a promus stent implantation and a coronary angioplasty. However, a month later, he developed fever followed by acute left ventricular failure and cardiac arrest. Thereafter, due to development of occluded circumflex artery and coronary aneurysm noted at the site of stent implantation, stent removal was performed. Subsequently, he was started on protracted antibiotic therapy with IV gentamicin 80mg three times a day [duration of treatment to reaction onset not stated], ceftazidime and vancomycin for Pseudomonas aeruginosa and Staphylococcus warneri infection. During the treatment, he developed ototoxicity. The man’s gentamicin therapy was discontinued after two weeks. Other antibiotics were continued for a period of six weeks. He recovered completely. Author comment: "After two weeks the gentamycin was stopped as he showed oto-toxicity." Dalal JJ, et al. Coronary stent infection - A grave, avoidable complication. IHJ Cardiovascular Case Reports (CVCR) 1: 77-79, No. 2, 2017. Available from: URL: - India 803285379 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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