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O.L. Kolomiets, M.M. Atsaeva, S.Ya. Dadashev (2013)
Damage to synaptonemal complex structure and peculiarities of selection of mouse spermatocytes I at response to drug administrationRuss. J. Genet., 49
P. Sutton, J. Perron, L.C. Giudice, T.J. Woodruff (2011)
Pesticides Matter: A Primer for Reproductive Health Physicians
M.A. Tavares, I.D.F. Palma, H.C.D. Medeiros (2015)
Comparative effects of fipronil and its metabolites sulfone and desulfinyl on the isolated rat liver mitochondriaEnviron. Toxicol. Pharmacol., 40
P. Møller (2005)
Genotoxicity of environmental agents assessed by the alkaline comet assayBasic Clin. Pharmacol. Toxicol., 96
O.L. Kolomiets, S.N. Matveevsky, I.Yu. Bakloushinskaya (2010)
Sexual dimorphism in prophase I of meiosis in mole vole (Ellobius talpinus Pallas) with isomorphic (XX) chromosomes in males and femalesComp. Cytogenet., 4
S. Sauvaigo, M. Bonnet-Duquennoy, F. Odin (2007)
DNA repair capacities of cutaneous fibroblasts: effect of sun exposureage and smoking on response to an acute oxidative stress, Br. J. Dermatol., 157
P.R. de Oliveira, G.H. Bechara, S.E. Denardi (2012)
Genotoxic and mutagenic effects of fipronil on miceExp. Toxicol. Pathol., 64
S.Zh. Kolumbaeva, D.A. Begimbetova, A.V. Lovinskaya, A.M. Kalimagambetov (2013)
Studies of the yellow ground squirrel (Citellus fulvus Licht.) in biotopes contaminated with phenylpyrazolesRuss. J. Ecol., 44
K. Madan (2012)
Balanced complex chromosome rearrangements: reproductive aspects: a reviewAm. J. Med. Genet., Part A, 158A
L.K. Anderson, A. Reeves, M.L. Webb, T. Ashley (1999)
Distribution of crossing over on mouse synaptonemal complexes using immunofluorescent localization of MLH1 proteinGenetics, 159
A. Çelik, G. Guler, S. Yildirim (2014)
In vitro genotoxicity of fipronil sister chromatid exchange, cytokinesis block micronucleus test, and comet assayDNA Cell Biol., 33
A.K. Zhanataev, A.D. Durnev, L.A. Oganesyants (2007)
Gel electrophoresis of isolated cells (comet assay) in the food gene toxicologyKhranenie Pererab. Sel’khozsyr’ya, 1
J. Navarro, F. Vidal, M. Quitart (1981)
A method for the sequental study of synaptonemal complex by light and electron microscopyHum. Genet., 59
K.G. Ordzhonikidze, A.M. Zanadvorova, S.K. Abilev (2011)
Organ specificity of the genotoxic effects of cyclophosphane and dioxidine: an alkaline comet assay studyRuss. J. Genet., 47
V.I. Lushchak (2014)
Free radicalsreactive oxygen species, oxidative stress and its classification, Chem.-Biol. Interact., 224
V. Tassistro, R. Ghalamoun-Slaimi, J. Saias-Magnan, M.-R. Guichaoua (2009)
Chronology of meiosis and synaptonemal complex abnormalities in normal and abnormal spermatogenesisIndian J. Med. Res., 129
A. Hartmann, E. Agurell, C. Beevers (2003)
Recommendations for conducting the in vivo alkaline comet assayMutagenesis, 18
D. Jackson, C.B. Cornell, B. Luukinen (2009)
National Pesticide Information Center Oregon State Univ. Extension Services
S.R. Belan, A.F. Trapov, G.M. Mel’nikova (2001)
Novye pestitsidy
S.Zh. Kolumbaeva, D.A. Begimbetova, A.V. Lovinskaya, A.M. Kalimagambetov (2012)
The content of the primary and secondary peroxidation products in laboratory rat liver when exposed to fipronil and fipronil sulfoneVestnik Kaz. Nats. Univ., Ser. Biol., 56
M.A. Fahmy (2002)
Cytogenetic studies on the effect of feeding mice with stored wheat grains treated with malathionMutat. Res., Genet. Toxicol. Environ. Mutagen., 513
S.Zh. Kolumbaeva, D.A. Begimbetova (2013)
Mutagennye effekty khimicheskikh zagryaznitelei okruzhayushchei sredy
D.A. Begimbetova, S.Zh. Kolumbaeva, A.M. Kalimagambetov (2008)
Genotoxic effects of fipronil on rats of different ages: 1. Fipronil sulfone effect in rats with acute exposureVestnik Kaz. Nats. Univ., Ser. Biol., 37
O.L. Kolomiets, N.K. Abuduev, T.F. Mazurova (2001)
Damaging effect of antibiotics on the structure of synaptonemal complexes of meiotic mouse chromosomesRuss. J. Genet., 37
A.S. Grafodatskii, S.I. Radzhabli (1988)
Khromosomy sel’skokhozyaistvennykh i laboratornykh mlekopitayushchikh
V. Moulisová, M. Srbová, O. Jedlicková, J. ebestian, A. Jegorov (2006)
Silibin reduces lipid peroxidation of rat hepatocyte membrane caused by cyclosporine ABiochemistry (Moscow), 71
S.K. Abilev, V.M. Glazer (2013)
Genetic toxicology: findings and challengesRuss. J. Genet., 49
U.B. Sorochinskaya, V.M. Mikhailenko (2008)
Application of the comet assay to assess DNA damage caused by a variety of environmental agentsOnkologiya, 10
A.D. Durnev (2008)
Methodological aspects of studies on chemical mutagenesis modificationByull. Eksp. Biol. Med., 146
A.K. Butorina, V.N. Kalaev (2000)
Analysis of sensitivity of different criteria in cytogenetic monitoringRuss. J. Ecol., 3
M.F. Guiraldelli, C. Eyster, J.L. Wilkerson (2013)
Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosisPLoS Genet., 9
The pronounced genotoxic effect of fipronil in all used doses (4.75, 9.50, 19.00, and 31.70 mg/kg) at a single exposure in the liver, lungs and spleen was ascertained by the Comet assay. Organ specificity of genotoxic effects of the pesticide was revealed. The liver was the most sensitive to fipronil. Fipronil at a dose of 9.50 mg/kg in a single and repeated exposure (within 10 days) induced aberrations in mouse bone marrow cells with the frequency exceeding the spontaneous mutation rate (p < 0.01 and p < 0.001, respectively). Fipronil also showed genotoxic activity in the germ cells of the experimental animals, causing abnormalities of the structure of synaptonemal complexes in the spermatocytes.
Russian Journal of Genetics – Springer Journals
Published: Jun 2, 2016
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