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/lp/springer_journal/genotoxic-effects-following-exposure-to-air-pollution-in-street-tZ0Q58itNF
- Publisher
- Springer International Publishing
- Copyright
- Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
- Subject
- Environment; Monitoring/Environmental Analysis; Environmental Management; Ecotoxicology; Atmospheric Protection/Air Quality Control/Air Pollution; Ecology
- ISSN
- 0167-6369
- eISSN
- 1573-2959
- D.O.I.
- 10.1007/s10661-018-6598-2
- Publisher site
- See Article on Publisher Site
Abstract
Workers in several occupational environments are exposed to pollutants. Street vendors, for example, typically work in a high-traffic urban environment and are exposed to numerous air pollutants, including genotoxic substances emitted by motor vehicles. This study examined the genotoxic effects of exposure to air pollution. We conducted cytological analyses to assess frequencies of micronucleated (MN) and binucleated (BN) cells in a sample of exfoliated oral mucosa cells. We compared street vendors and control subjects in the city of Uberlândia, Minas Gerais, Brazil, and also collected quantitative information on exposure conditions of all test subjects, including concentrations of particulate matter. We found street vendors to exhibit higher frequencies of MN cells compared to the control group. We evaluated the effects of possible confounding variables on MN frequencies, namely the body mass index (BMI), age, as well as smoking and alcohol habits. Multiple linear regression analysis found no significant effects of any of those variables. Our results suggest that continued exposure to air pollution from traffic represents a major source of genotoxicity and raises concerns regarding disease prevention not only in street vendors but also other groups of people working in urban environments.
Journal
Environmental Monitoring and Assessment – Springer Journals
Published: Mar 14, 2018
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