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M. Söderlund, R. Essen, J. Haapasaari, U. Kiistala, O. Kiviluoto, K. Hedman (1997)
Persistence of parvovirus B19 DNA in synovial membranes of young patients with and without chronic arthropathyThe Lancet, 349
Xuewen Deng, H. Terunuma, R. Handema, M. Sakamoto, T. Kitamura, Masahiko Ito, Y. Akahane (2000)
Higher prevalence and viral load of TT virus in saliva than in the corresponding serum: Another possible transmission route and replication site of TT virusJournal of Medical Virology, 62
P. Chan, K. Chik, K. To, C. Li, M. Hui, M. Shing, P. Yuen, J. Tam, A. Cheng (2001)
Clearance of TT virus after allogeneic bone marrow transplantation.Journal of pediatric hematology/oncology, 23 1
A. Eis-Hübinger, U. Reber, Thair Abdul-Nour, U. Glatzel, H. Lauschke, U. Pütz (2001)
Evidence for persistence of parvovirus B19 DNA in livers of adultsJournal of Medical Virology, 65
H. Okamoto, M. Ukita, T. Nishizawa, J. Kishimoto, Y. Hoshi, H. Mizuo, Takeshi Tanaka, Y. Miyakawa, M. Mayumi (2000)
Circular Double-Stranded Forms of TT Virus DNA in the LiverJournal of Virology, 74
H. Okamoto, Masaharu Takahashi, T. Nishizawa, M. Ukita, M. Fukuda, F. Tsuda, Yuzo Miyakawa, Makoto Mayumi (1999)
Marked genomic heterogeneity and frequent mixed infection of TT virus demonstrated by PCR with primers from coding and noncoding regions.Virology, 259 2
M. Pistello, A. Morrica, F. Maggi, M. Vatteroni, G. Freer, C. Fornai, F. Casula, S. Marchi, P. Ciccorossi, P. Rovero, M. Bendinelli (2001)
TT virus levels in the plasma of infected individuals with different hepatic and extrahepatic pathologyJournal of Medical Virology, 63
J. Ball, R. Curran, Selina Berridge, A. Grabowska, C. Jameson, B. Thomson, W. Irving, P. Sharp (1999)
TT virus sequence heterogeneity in vivo: evidence for co-infection with multiple genetic types.The Journal of general virology, 80 ( Pt 7)
F. Maggi, M. Pifferi, C. Fornai, E. Andreoli, E. Tempestini, M. Vatteroni, S. Presciuttini, S. Marchi, A. Pietrobelli, A. Boner, M. Pistello, M. Bendinelli (2003)
TT Virus in the Nasal Secretions of Children with Acute Respiratory Diseases: Relations to Viremia and Disease SeverityJournal of Virology, 77
C. Kurihara, N. Ishiyama, Y. Nishiyama, K. Katayama, S. Miura (2001)
Changes of DNA titer and sequence variance of TT virus in hepatic disorders.Hepatology research : the official journal of the Japan Society of Hepatology, 19 3
C.‐L. Lin, W. Kyono, J. Tongson, P. Chua, D. Easa, Richard Yanagihara, Vivek Nerurkar (2000)
Fecal Excretion of a Novel Human Circovirus, TT Virus, in Healthy ChildrenClinical Diagnostic Laboratory Immunology, 7
H. Okamoto, M. Mayumi (2001)
TT virus: virological and genomic characteristics and disease associationsJournal of Gastroenterology, 36
B. Meehan, F. Mcneilly, D. Todd, S. Kennedy, V. Jewhurst, J. Ellis, L. Hassard, E. Clark, D. Haines, G. Allan (1998)
Characterization of novel circovirus DNAs associated with wasting syndromes in pigs.The Journal of general virology, 79 ( Pt 9)
T. Nishizawa, H. Okamoto, K. Konishi, H. Yoshizawa, Y. Miyakawa, M. Mayumi (1997)
A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology.Biochemical and biophysical research communications, 241 1
M. Schröter, S. Polywka, B. Zöllner, P. Schäfer, R. Laufs, H. Feucht (2000)
Detection of TT Virus DNA and GB Virus Type C/Hepatitis G Virus RNA in Serum and Breast Milk: Determination of Mother-to-Child TransmissionJournal of Clinical Microbiology, 38
T. Pollicino, G. Raffa, G. Squadrito, L. Costantino, I. Cacciola, S. Brancatelli, C. Alafaci, M. Florio, G. Raimondo (2003)
TT virus has a ubiquitous diffusion in human body tissues: analyses of paired serum and tissue samplesJournal of Viral Hepatitis, 10
F. Maggi, C. Fornai, L. Zaccaro, A. Morrica, M. Vatteroni, P. Isola, S. Marchi, A. Ricchiuti, M. Pistello, M. Bendinelli (2001)
TT virus (TTV) loads associated with different peripheral blood cell types and evidence for TTV replication in activated mononuclear cellsJournal of Medical Virology, 64
P. Simmonds, L. Prescott, C. Logue, F. Davidson, A. Thomas, C. Ludlam (1999)
TT virus--part of the normal human flora?The Journal of infectious diseases, 180 5
F., McOMISH, P. Yap, '. Jordan, '. Hart, B. Cohen, P. Simmonds (1993)
Detection of parvovirus B19 in donated blood: a model system for screening by polymerase chain reactionJournal of Clinical Microbiology, 31
C. Fornai, F. Maggi, M. Vatteroni, M. Pistello, M. Bendinelli (2001)
High Prevalence of TT Virus (TTV) and TTV-Like Minivirus in Cervical SwabsJournal of Clinical Microbiology, 39
P. Ernst, B. Gold (2000)
The disease spectrum of Helicobacter pylori: the immunopathogenesis of gastroduodenal ulcer and gastric cancer.Annual review of microbiology, 54
H. Okamoto, Masaharu Takahashi, N. Kato, Masako Fukuda, A. Tawara, S. Fukuda, Takeshi Tanaka, Y. Miyakawa, M. Mayumi (2000)
Sequestration of TT Virus of Restricted Genotypes in Peripheral Blood Mononuclear CellsJournal of Virology, 74
P. Chan, K. Chik, C.‐K. Li, N. Tang, M. Ming, J. Cheung, K. Ng, P. Yuen, A. Cheng (2001)
Prevalence and genotype distribution of TT virus in various specimen types from thalassaemic patientsJournal of Viral Hepatitis, 8
T. Ishikawa, Y. Hamano, H. Okamoto (1999)
Frequent detection of TT virus in throat swabs of pediatric patients.Infection, 27 4-5
G. Masia, A. Ingianni, L. Demelia, G. Faa, P. Manconi, G. Pilleri, A. Ciancio, M. Rizzetto, R. Coppola (2001)
TT virus infection in Italy: prevalence and genotypes in healthy subjects, viral liver diseases and asymptomatic infections by parenterally transmitted virusesJournal of Viral Hepatitis, 8
S. Zhong, W. Yeo, Mandy Tang, Cuiling Liu, Xiao‐rong Lin, W. Ho, P. Hui, P. Johnson (2002)
Frequent detection of the replicative form of TT virus DNA in peripheral blood mononuclear cells and bone marrow cells in cancer patientsJournal of Medical Virology, 66
D. Hirata, N. Kaneko, M. Iwamoto, T. Yoshio, H. Okazaki, A. Mimori, J. Masuyama, S. Minota (1998)
Infection with an unenveloped DNA virus (TTV) associated with non-A to G hepatitis in patients with rheumatoid arthritis.British journal of rheumatology, 37 12
M. Comar, F. Ansaldi, L. Morandi, G. Molin, P. Foschini, S. Croce’, S. Bonin, G. Stanta, C. Tiribelli, C. Campello (2002)
In situ polymerase chain reaction detection of transfusion‐transmitted virus in liver biopsyJournal of Viral Hepatitis, 9
L. Kaikkonen, H. Lankinen, I. Harjunpää, K. Hokynar, M. Söderlund-Venermo, C. Oker‐Blom, L. Hedman, K. Hedman (1999)
Acute-Phase-Specific Heptapeptide Epitope for Diagnosis of Parvovirus B19 InfectionJournal of Clinical Microbiology, 37
P. Gallian, P. Biagini, S. Zhong, M. Touinssi, Winnie Yeo, J. Cantaloube, H. Attoui, P. Micco, Philip Johnson, Xavier Lamballerie (2000)
TT virus: a study of molecular epidemiology and transmission of genotypes 1, 2 and 3.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 17 1
G. Kingsley (1997)
Microbial DNA in the synovium—a role in aetiology or a mere bystander?The Lancet, 349
T. Ikeuchi, O. Yokosuka, T. Kanda, F. Imazeki, T. Seta, H. Saisho (2001)
Roles of TT Virus Infection in Various Types of Chronic HepatitisIntervirology, 44
C. Osiowy, C. Sauder (2000)
Detection of TT virus in human hair and skinHepatology Research, 16
H. Matsubara, K. Michitaka, N. Horiike, Mariko Yano, S. Akbar, M. Torisu, M. Onji (2000)
Existence of TT Virus DNA in Extracellular Body Fluids from Normal Healthy Japanese SubjectsIntervirology, 43
Masaharu Takahashi, S. Asabe, Y. Gotanda, J. Kishimoto, F. Tsuda, H. Okamoto (2002)
TT virus is distributed in various leukocyte subpopulations at distinct levels, with the highest viral load in granulocytes.Biochemical and biophysical research communications, 290 1
L. Mariscal, J. López-Alcorocho, E. Rodríguez-Iñigo, N. Ortiz‐Movilla, S. Lucas, J. Bartolomé, V. Carreño (2002)
TT virus replicates in stimulated but not in nonstimulated peripheral blood mononuclear cells.Virology, 301 1
H. Okamoto, Y. Akahane, M. Ukita, M. Fukuda, F. Tsuda, Y. Miyakawa, M. Mayumi (1998)
Fecal excretion of a nonenveloped DNA virus (TTV) associated with posttransfusion non‐A‐G hepatitisJournal of Medical Virology, 56
T. Vuorinen, K. Lammintausta, P. Kotilainen, S. Nikkari (2002)
Presence of parvovirus B19 DNA in chronic urticaric and healthy human skin.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 25 2
J. Lefrère, Françoise Roudot-Thoraval, François Lefrère, Alain Kanfer, M. Mariotti, J. Lerable, M. Thauvin, Guillaume Lefèvre, Philippe Rouger, Robert Girot (2000)
Natural history of the TT virus infection through follow-up of TTV DNA-positive multiple-transfused patients.Blood, 95 1
J. López-Alcorocho, L. Mariscal, S. Lucas, E. Rodríguez-Iñigo, M. Casqueiro, I. Castillo, J. Bartolomé, M. Herrero, M. Manzano, M. Pardo, V. Carreño (2000)
Presence of TTV DNA in serum, liver and peripheral blood mononuclear cells from patients with chronic hepatitisJournal of Viral Hepatitis, 7
M. Ukita, H. Okamoto, N. Kato, Y. Miyakawa, M. Mayumi (1999)
Excretion into bile of a novel unenveloped DNA virus (TT virus) associated with acute and chronic non-A-G hepatitis.The Journal of infectious diseases, 179 5
L. Kakkola, K. Hedman, Heidi Vanrobaeys, L. Hedman, M. Söderlund-Venermo (2002)
Cloning and sequencing of TT virus genotype 6 and expression of antigenic open reading frame 2 proteins.The Journal of general virology, 83 Pt 5
E. Rodríguez-Iñigo, M. Casqueiro, J. Bartolomé, N. Ortiz‐Movilla, J. López-Alcorocho, M. Herrero, F. Manzarbeitia, Horacio Oliva, V. Carreño (2000)
Detection of TT virus DNA in liver biopsies by in situ hybridization.The American journal of pathology, 156 4
H. Tokita, S. Murai, H. Kamitsukasa, M. Yagura, H. Harada, Masaharu Takahashi, H. Okamoto (2002)
High TT virus load as an independent factor associated with the occurrence of hepatocellular carcinoma among patients with hepatitis C virus‐related chronic liver diseaseJournal of Medical Virology, 67
Saal Jg, M. Steidle, Hermann Einsele, C. Müller, P. Fritz, J. Zacher (2004)
Persistence of B19 parvovirus in synovial membranes of patients with rheumatoid arthritisRheumatology International, 12
Florian Heller, R. Zachoval, Anja Koelzer, H. Nitschko, G. Froesner (2001)
Isolate KAV: a new genotype of the TT-virus family.Biochemical and biophysical research communications, 289 5
E. Rodríguez-Iñigo, J. Arrieta, M. Casqueiro, J. Bartolomé, J. López-Alcorocho, N. Ortiz‐Movilla, F. Manzarbeitia, M. Pardo, V. Carreño (2001)
TT virus detection in oral lichen planus lesionsJournal of Medical Virology, 64
F. Suzuki, K. Chayama, A. Tsubota, N. Akuta, T. Someya, M. Kobayashi, Yoshiyuki Suzuki, S. Saitoh, Y. Arase, K. Ikeda, H. Kumada (2001)
Pathogenic Significance and Organic Virus Levels in Patients Infected with TT VirusIntervirology, 44
I. Mushahwar, J. Erker, A. Muerhoff, T. Leary, J. Simons, L. Birkenmeyer, M. Chalmers, T. Pilot-matias, Dexai Sm (1999)
Molecular and biophysical characterization of TT virus: evidence for a new virus family infecting humans.Proceedings of the National Academy of Sciences of the United States of America, 96 6
C. Niel, F. Saback, E. Lampe (2000)
Coinfection with Multiple TT Virus Strains Belonging to Different Genotypes Is a Common Event in Healthy Brazilian AdultsJournal of Clinical Microbiology, 38
N. Nakagawa, J. Ikoma, T. Ishihara, Noriko Yasui‐Kawamura, N. Fujita, M. Iwasa, M. Kaito, Shozo Watanabe, Y. Adachi (2000)
Biliary excretion of TT virus (TTV)Journal of Medical Virology, 61
P. Saikku (2000)
Chlamydia pneumoniae in atherosclerosisJournal of Internal Medicine, 247
M. Bendinelli, M. Pistello, F. Maggi, C. Fornai, G. Freer, M. Vatteroni (2001)
Molecular Properties, Biology, and Clinical Implications of TT Virus, a Recently Identified Widespread Infectious Agent of HumansClinical Microbiology Reviews, 14
H. Okamoto, T. Nishizawa, N. Kato, M. Ukita, H. Ikeda, H. Iizuka, Y. Miyakawa, M. Mayumi (1998)
Molecular cloning and characterization of a novel DNA virus (TTV) associated with posttransfusion hepatitis of unknown etiologyHepatology Research, 10
(2002)
A (2002) TT virus infection and genotype distribution in blood donors and a group of patients
K. Hokynar, M. Söderlund-Venermo, M. Pesonen, A. Ranki, O. Kiviluoto, E. Partio, K. Hedman (2002)
A new parvovirus genotype persistent in human skin.Virology, 302 2
H. Okamoto, T. Nishizawa, Masaharu Takahashi, S. Asabe, F. Tsuda, A. Yoshikawa (2001)
Heterogeneous distribution of TT virus of distinct genotypes in multiple tissues from infected humans.Virology, 288 2
(1999)
1999)Acute-phase-specific heptapeptide epitope for diagnosis of parvovirus B19 infection
F. Maggi, C. Fornai, M. Vatteroni, G. Siciliano, F. Menichetti, C. Tascini, S. Specter, M. Pistello, M. Bendinelli (2001)
Low prevalence of TT virus in the cerebrospinal fluid of viremic patients with central nervous system disordersJournal of Medical Virology, 65
H. Okamoto, Masaharu Takahashi, T. Nishizawa, A. Tawara, Y. Sugai, T. Sai, Takeshi Tanaka, F. Tsuda (2000)
Replicative forms of TT virus DNA in bone marrow cells.Biochemical and biophysical research communications, 270 2
S. Erensoy, A. Sayıner, S. Türkoğlu, D. Canatan, U. Akarca, R. Sertöz, T. Özacar, Y. Batur, S. Badur, A. Bilgiç (2002)
TT Virus Infection and Genotype Distribution in Blood Donors and a Group of Patients from TurkeyInfection, 30
Y. Peng, T. Nishizawa, Masaharu Takahashi, T. Ishikawa, A. Yoshikawa, H. Okamoto (2002)
Analysis of the entire genomes of thirteen TT virus variants classifiable into the fourth and fifth genetic groups, isolated from viremic infantsArchives of Virology, 147
P. Gerner, R. Oettinger, Wibke Gerner, J. Falbrede, S. Wirth (2000)
Mother-to-infant transmission of TT virus: prevalence, extent and mechanism of vertical transmission.The Pediatric infectious disease journal, 19 11
M. Söderlund-Venermo, K. Hokynar, J. Nieminen, H. Rautakorpi, K. Hedman (2002)
Persistence of human parvovirus B19 in human tissues.Pathologie-biologie, 50 5
S. Hino (2002)
TTV, a new human virus with single stranded circular DNA genomeReviews in Medical Virology, 12
K. Abe, T. Inami, Kazue Asano, C. Miyoshi, N. Masaki, S. Hayashi, K. Ishikawa, Y. Takebe, K. Win, A. El‐Zayadi, Kwang‐hyub Han, David Zhang (1999)
TT Virus Infection Is Widespread in the General Populations from Different Geographic RegionsJournal of Clinical Microbiology, 37
TT virus (TTV) is a newly discovered human virus of high genotypic diversity. TTV is widely distributed among humans, but the possible genotype-related differences in TTV biology are not well known. The prevalence and amount of TTV-DNA, especially of genotype 6, was determined by nested-PCR in various human tissues, and human parvovirus B19, another ssDNA virus, was used as a reference. TTV DNA was detected simultaneously in bile, peripheral blood mononuclear cells (PBMC) and plasma of 77% subjects, in 38% skin samples, in 38% synovial samples and in all (100%) adenoids, tonsils and liver samples. The relative concentrations of TTV-DNA did not vary significantly among the different samples. Genotype 6 TTV-DNA was detected in bile and plasma of one subject (3%), in skin and serum of one subject (8%) and in one liver (5%). The overall prevalence of TTV genotype 6 was 4% in subjects and 4% in sera. TTV genotype 6 was shown to occur in human tissues with no obvious tissue-type or symptom specificity. Parvovirus B19 DNA was detected overall in 38% subjects, and bile was the only sample type tested that did not persistently harbour B19 DNA.
Archives of Virology – Springer Journals
Published: Jun 1, 2004
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