Mammalian Genome 10, 1023–1025 (1999). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1999 Genomic structure, cDNA mapping, and chromosomal localization of the mouse homeobox gene, Hex 1 1 2 2 2 Bidyut Ghosh, Harris C. Jacobs, Leanne M. Wiedemann, Anthony Brown, Fiona K. Bedford, 3 3 1 Manjunath A. Nimmakayalu, David C. Ward, Clifford W. Bogue Section of Critical Care and Applied Physiology, Department of Pediatrics, Yale University School of Medicine, P.O. Box 208064, 333 Cedar Street, New Haven, Connecticut 06520-8064, USA Leukemia Research Fund Centre at the Institute of Cancer Research, Chester Beatty Laboratories, London, UK Department of Genetics, Yale University School of Medicine, New Haven, Connecticut 06520, USA Received: 16 April 1999 / Accepted: 24 May 1999 Homeobox genes constitute a large family of transcription factors 38 end of the Hex cDNA was determined by 38 RACE (Rapid that regulate different aspects of cell differentiation and morpho- Amplification of cDNA Ends) with a kit from Clontech Labora- genesis during development (Wright et al. 1989; Gehring et al. tories, Inc. (Palo Alto, CA) following the manufacturer’s instruc- 1994). They are distinguished by a 180-bp, evolutionarily con- tions. An adapter-specific antisense primer AP1 (5 8 - served DNA-binding
Mammalian Genome – Springer Journals
Published: Oct 1, 1999
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