Genomic organization of human B-ATF, a target for regulation by EBV and HTLV-1

Genomic organization of human B-ATF, a target for regulation by EBV and HTLV-1 Mammalian Genome 9, 849–852 (1998). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1998 Genomic organization of human B-ATF, a target for regulation by EBV and HTLV-1 Ne ´va P. Meyer, Lisa M. Johansen, Hyi-Jeong Tae, Priya P. Budde, Kristi L. Williams, Elizabeth J. Taparowsky Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907-1392, USA Received: 22 December 1997 / Accepted: 29 May 1998 The human B-ATF cDNA was isolated originally from an Epstein- Barr virus (EBV)-stimulated B lymphocyte cDNA library (Dorsey et al. 1995). Subsequent analysis of a variety of human tissues and cell lines revealed exclusive expression of the estimated 940-base B-ATF mRNA in tissues of hematopoietic origin, with the highest levels detected in EBV-positive human B cell lines such as Raji Burkitt’s lymphoma (Dorsey et al. 1995) and 721 (Fig. 1A; Dorsey et al. 1995). EBV-negative human B cells, including the BJAB cell line and primary human B lymphocytes, do not express B-ATF until infected with biologically active EBV (Fig. 1A and data not shown). Recent studies from the lab demonstrate that within 24 h of infecting resting human B cells with biologically active EBV, B-ATF mRNA is induced 25-fold, suggesting that the induction of Mammalian Genome Springer Journals

Genomic organization of human B-ATF, a target for regulation by EBV and HTLV-1

Loading next page...
Copyright © 1998 by Springer-Verlag New York Inc.
Life Sciences; Cell Biology; Animal Genetics and Genomics; Human Genetics
Publisher site
See Article on Publisher Site

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial