Short Communications Mammalian Genome 8, 767–769 (1997). © Springer-Verlag New York Inc. 1997 Genomic organization of Ampd3, heart-type AMPD gene, located in mouse Chromosome 7 1 1 2 2 1 1 1 K. Sermsuvitayawong, X. Wang, A. Nagabukuro, Y. Matsuda, H. Morisaki, K. Toyama, T. Mukai, T. Morisaki Department of Bioscience, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita, Osaka 565, Japan Laboratory of Animal Genetics, School of Agricultural Sciences, University of Nagoya, Chikusa, Nagoya 464-01, Japan Received: 12 January 1997 / Accepted: 8 June 1997 AMP deaminase (EC 18.104.22.168., AMPD), an enzyme catalyzing AMP into IMP, plays an important role in purine metabolism, especially in skeletal muscle, since metabolic myopathy associated with AMPD deficiency has been reported (Sabina and Holmes 1995). In higher eukaryotes, several isoenzymes of AMPD are encoded in separate genes (Sabina and Holmes 1995; Morisaki et al. 1990; Mahnke-Zizelman and Sabina 1992). Among three ro- dent Ampd genes, Ampd3 gene, gene for the heart-type isoform (H-isoform) of AMPD, which is expressed in heart, slow-twitch skeletal muscles and non-muscle tissues (Wang et al. 1997), has not been well studied, whereas Ampd1, encoding the M-isoform, has been extensively characterized (Morisaki et al. 1990). Under- standing the Ampd3
Mammalian Genome – Springer Journals
Published: Oct 1, 1997
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera