Genomic dosages of active rRNA genes in coke-oven workers

Genomic dosages of active rRNA genes in coke-oven workers Genomic dosage (copy number) of active ribosomal genes was evaluated using visual semi-quantitative method determining the sizes of Ag-NORs in acrocentric chromosomes after selective silver nitrate staining. A relationship between the length of service and the active ribosomal gene copy number was established: the highest numbers of active rRNA genes were observed in coke-oven workers with a length of service exceeding 20 years. An inverse relationship between the individual doses of active ribosomal genes and toxicogenetic susceptibility of the workers to the occupational factors was also revealed. Russian Journal of Genetics Springer Journals

Genomic dosages of active rRNA genes in coke-oven workers

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Copyright © 2004 by MAIK “Nauka/Interperiodica”
Biomedicine; Human Genetics; Microbial Genetics and Genomics; Animal Genetics and Genomics
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