Genomic characterization and evolution analysis of a mutant reovirus isolated from grass carp in Anhui

Genomic characterization and evolution analysis of a mutant reovirus isolated from grass carp in... Arch Virol (2016) 161:1385–1387 DOI 10.1007/s00705-016-2754-6 ANNOTATED SEQUENCE RECORD Genomic characterization and evolution analysis of a mutant reovirus isolated from grass carp in Anhui 1 1 1 1 1 • • • • • Minglin Wu Kai Cui Haiyang Li Jixiang He Honglian Chen 1 1 Yangyang Jiang Jun Ren Received: 13 October 2015 / Accepted: 2 January 2016 / Published online: 13 January 2016 Springer-Verlag Wien 2016 Grass carp fingerlings and yearlings are vulnerable to grass 3], the GCRV-AH528 S1 segment had lost three continu- carp reovirus (GCRV), leading to a mortality rate of more ous nucleotides (TAT) at nt 701-702, leading to the loss of than 80 %. A virulent reovirus, tentatively named GCRV- a tyrosine, and the S4 segment exhibited two ORFs AH528, was isolated from a diseased grass carp in Anhui encoding two proteins, indicating that GCRV-AH528 was Province, China, in 2014. The isolated virus could be distinct from any known GCRV and was a mutant reovirus. propagated in Ctenopharyngodon idellus kidney cells. Sequence comparisons showed that GCRV-AH528 pos- However, the typical cytopathic effects of aquareovirus sessed only seven proteins that were homologous to those infection were not observed with this strain. Intraperitoneal of the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Genomic characterization and evolution analysis of a mutant reovirus isolated from grass carp in Anhui

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Publisher
Springer Vienna
Copyright
Copyright © 2016 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-016-2754-6
Publisher site
See Article on Publisher Site

Abstract

Arch Virol (2016) 161:1385–1387 DOI 10.1007/s00705-016-2754-6 ANNOTATED SEQUENCE RECORD Genomic characterization and evolution analysis of a mutant reovirus isolated from grass carp in Anhui 1 1 1 1 1 • • • • • Minglin Wu Kai Cui Haiyang Li Jixiang He Honglian Chen 1 1 Yangyang Jiang Jun Ren Received: 13 October 2015 / Accepted: 2 January 2016 / Published online: 13 January 2016 Springer-Verlag Wien 2016 Grass carp fingerlings and yearlings are vulnerable to grass 3], the GCRV-AH528 S1 segment had lost three continu- carp reovirus (GCRV), leading to a mortality rate of more ous nucleotides (TAT) at nt 701-702, leading to the loss of than 80 %. A virulent reovirus, tentatively named GCRV- a tyrosine, and the S4 segment exhibited two ORFs AH528, was isolated from a diseased grass carp in Anhui encoding two proteins, indicating that GCRV-AH528 was Province, China, in 2014. The isolated virus could be distinct from any known GCRV and was a mutant reovirus. propagated in Ctenopharyngodon idellus kidney cells. Sequence comparisons showed that GCRV-AH528 pos- However, the typical cytopathic effects of aquareovirus sessed only seven proteins that were homologous to those infection were not observed with this strain. Intraperitoneal of the

Journal

Archives of VirologySpringer Journals

Published: May 1, 2016

References

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