Genetically Controlled Expression of Surface Variant Antigens in Free-Living Protozoa

Genetically Controlled Expression of Surface Variant Antigens in Free-Living Protozoa J. Membrane Biol. 180, 101–109 (2001) The Journal of DOI: 10.1007/s002320010062 Membrane Biology © Springer-Verlag New York Inc. 2001 Topical Review J. Kusch, H.J. Schmidt Department of Biology, University of Kaiserslautern, 67663 Kaiserslautern, Germany Received: 19 June 2000/Revised: 6 September 2000 Introduction immobilization via antibodies. These cells induce the production of a different type of antibody after their in- jection into mammals. The cells represent a further se- Besides parasitic protozoa some free-living ciliates have rotype within the ciliate clone. In this way a range of the ability to exhibit alternative types of proteins on their serotypes, corresponding to different surface antigens, cell surface (Sonneborn, 1948; reviews: Schmidt, 1988; was observed in several species of Paramecium and of Bleyman, 1996; Schmidt, 1996). A range of these ex- Tetrahymena (Nanney & Dubert, 1960; Koizumi, 1966; changeable structurally different surface proteins has Hiwatashi, 1967; Juergensmeyer, 1969; Sonneborn, been detected in species of the genera Paramecium (Cili- 1974; Steers & Barnett, 1982). Seven different serotypes ophora) and Tetrahymena (Ciliophora). The presence of are known for Paramecium primaurelia and twelve for variable surface proteins is detected by immunochemical P. tetraurelia. Most of the known strains of these spe- techniques. Injections of Paramecia or http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Membrane Biology Springer Journals

Genetically Controlled Expression of Surface Variant Antigens in Free-Living Protozoa

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Publisher
Springer-Verlag
Copyright
Copyright © Inc. by 2001 Springer-Verlag New York
Subject
Life Sciences; Biochemistry, general; Human Physiology
ISSN
0022-2631
eISSN
1432-1424
D.O.I.
10.1007/s002320010062
Publisher site
See Article on Publisher Site

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