Genetic Mechanisms of Virulence in Listeria monocytogenes

Genetic Mechanisms of Virulence in Listeria monocytogenes Current data on genetic determinants of virulence in Listeria monocytogenesand on factors affecting their expression are reviewed. The role of the PrfA protein, the only known transcriptional regulator that directly affects virulence gene expression and mechanisms responsible for the activity and/or concentration of this protein in the cell are considered. Detailed information of external signals modulating the level of virulence factor expression is provided. Data that favor the involvement of autoregulatory processes in the expression of virulence genes are considered, and a model of regulation to explain these data is proposed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Genetic Mechanisms of Virulence in Listeria monocytogenes

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Publisher
Springer Journals
Copyright
Copyright © 2001 by MAIK “Nauka/Interperiodica”
Subject
Biomedicine; Human Genetics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1023/A:1009044707398
Publisher site
See Article on Publisher Site

Abstract

Current data on genetic determinants of virulence in Listeria monocytogenesand on factors affecting their expression are reviewed. The role of the PrfA protein, the only known transcriptional regulator that directly affects virulence gene expression and mechanisms responsible for the activity and/or concentration of this protein in the cell are considered. Detailed information of external signals modulating the level of virulence factor expression is provided. Data that favor the involvement of autoregulatory processes in the expression of virulence genes are considered, and a model of regulation to explain these data is proposed.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Oct 12, 2004

References

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