Genetic mapping of Afr2 (Rif): regulator of gene expression in liver regeneration

Genetic mapping of Afr2 (Rif): regulator of gene expression in liver regeneration Mammalian Genome 9, 256-258 (1998). Mymmafian Genome Incorporating Mouee Genome © Springer-Verlag New York Inc. 1998 Genetic mapping of Afr2 (Rif): regulator of gene expression in liver regeneration David K. Jin, Miriam H. Feuerman Department of Biochemistry, Box 8, State University of New York, Health Science Center at Brooklyn, 450 Clarkson Avenue, Brooklyn, New York 11203, USA Received: 21 October 1997 / Accepted: 17 November 1997 Alpha-fetoprotein (AFP) is a classic oncofetal antigen. The AFP lation should have the paternal C3H/HeJ-specific sequence, serv- gene is highly expressed during gestation in the visceral endoderm ing as a positive control for the assay. SSLP markers genetically of yolk sac, fetal liver, and the gastrointestinal tract (Andrews et al. linked to Afr2 would yield a higher frequency of the C57BL/6J 1982; Tilghman and Belayew 1982), but is repressed to an almost sequence relative to the C3H/HeJ sequence in the low AFP- undetectable level in the adult liver (Tilghman and Belayew 1982). expressing population. The D2Mit2O8 locus was closely linked to Expression of the AFP gene can be re-activated in response to liver Afr2 as all the high AFP-expressing mice were Afr2^a homozy- regeneration induced by partial hepatectomy or acute carbon tet- gotes, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Genetic mapping of Afr2 (Rif): regulator of gene expression in liver regeneration

Loading next page...
 
/lp/springer_journal/genetic-mapping-of-afr2-rif-regulator-of-gene-expression-in-liver-4SbYQ2ge1G
Publisher
Springer-Verlag
Copyright
Copyright © 1998 by Springer-Verlag
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003359900738
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial