Genetic diversities and phylogenetic analysis of 18 autosomal STR loci in the Uyghur population living in Ili, Northwest China

Genetic diversities and phylogenetic analysis of 18 autosomal STR loci in the Uyghur population... Ili is located in northernmost Xinjiang, China. The Uyghur population only accounts for 15.90% of the total population in the nation. There is currently no large population data-based data set in Ili Uyghur. In this study, we investigated the genetic diversities of 18 autosomal short tandem repeat (STR) loci in 1129 Uyghur individuals living in Ili. The values of combined power of discrimination (CPD) and combined probability of exclusion (CPE) were 0.99999999999999999999990244 and 0.99999995645, respectively. Furthermore, we explored the genetic relationships between the Ili Uyghur population and 32 previously published populations. The results indicated that the Ili Uyghur population was more closely related to the Xinjiang Kazakh population. In addition, It was worth noting that significant differences were observed between Ili the Uyghur population and the Uyghur1 and Uyghur2 populations at the shared 15 loci, with significant differences at 7 and 11 loci after Bonferroni adjustment (p =0.05/495 ≈ 0.00010). . . . Keywords Genetic polymorphisms Short tandem repeat Uyghur population Ili Ili is located in the northernmost part Xinjiang, China (Fig. by the Ethics Committee of the Institute of Forensic Science, S1) and it is south of Russia, west of Mongolia, and east of Ministry of Public Security, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Journal of Legal Medicine Springer Journals

Genetic diversities and phylogenetic analysis of 18 autosomal STR loci in the Uyghur population living in Ili, Northwest China

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2018 by Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Medicine & Public Health; Forensic Medicine; Medical Law; Medicine/Public Health, general
ISSN
0937-9827
eISSN
1437-1596
D.O.I.
10.1007/s00414-018-1872-y
Publisher site
See Article on Publisher Site

Abstract

Ili is located in northernmost Xinjiang, China. The Uyghur population only accounts for 15.90% of the total population in the nation. There is currently no large population data-based data set in Ili Uyghur. In this study, we investigated the genetic diversities of 18 autosomal short tandem repeat (STR) loci in 1129 Uyghur individuals living in Ili. The values of combined power of discrimination (CPD) and combined probability of exclusion (CPE) were 0.99999999999999999999990244 and 0.99999995645, respectively. Furthermore, we explored the genetic relationships between the Ili Uyghur population and 32 previously published populations. The results indicated that the Ili Uyghur population was more closely related to the Xinjiang Kazakh population. In addition, It was worth noting that significant differences were observed between Ili the Uyghur population and the Uyghur1 and Uyghur2 populations at the shared 15 loci, with significant differences at 7 and 11 loci after Bonferroni adjustment (p =0.05/495 ≈ 0.00010). . . . Keywords Genetic polymorphisms Short tandem repeat Uyghur population Ili Ili is located in the northernmost part Xinjiang, China (Fig. by the Ethics Committee of the Institute of Forensic Science, S1) and it is south of Russia, west of Mongolia, and east of Ministry of Public Security,

Journal

International Journal of Legal MedicineSpringer Journals

Published: May 31, 2018

References

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