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G Panasiewicz, M Majewska, A Romanowska, J Dajnowiec, B Szafranska (2007)
Radiocompetition of secretory pregnancy-associated glycoproteins as chorionic ligands with luteal and uterine gonadotrophin receptors of pregnant pigsAnim Reprod Sci, 99
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Suprafamilial relationships among Rodentia and the phylogenetic effect of removing fast-evolving nucleotides in mitochondrial, exon and intron fragmentsBMC Evol Biol, 8
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Biodiversity of multiple pregnancy-associated glycoprotein (PAG) family: gene cloning and chorionic protein purification in domestic and wild eutherians (Placentalia)—a reviewReprod Nutr Dev, 5
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Porcine pregnancy-associated glycoproteins: new members of the aspartic proteinase gene family expressed in trophectodermBiol Reprod, 53
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Pregnancy-associated glycoprotein (PAG) family: transcripts and gene amplicons in camelidsReprod Biol, 9
M Bieniek-Kobuszewska, G Panasiewicz, A Lipka, M Majewska, B Szafranska (2016)
Novel SNPs and InDels discovered in two promoter regions of porcine pregnancy-associated glycoprotein 2-like subfamily (pPAG2-ls) in cross-breed pigsFunct Integ Genomics, 16
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G Panasiewicz, M Majewska, B Szafranska (2004)
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B Szafranska, G Panasiewicz, M Majewska, A Romanowska, J Dajnowiec (2007)
Pregnancy-associated glycoprotein family (PAG)—as chorionic signaling ligands for gonadotropin receptors of cyclic animalsAnim Reprod Sci, 99
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B Szafranska, R Miura, D Ghosh, T Ezashi, S Xie, RM Roberts, JA Green (2001)
Gene for porcine pregnancy-associated glycoprotein 2 (poPAG2): its structural organization and analysis of its promoterMol Reprod Dev, 60
RM Wallace, KG Pohler, MF Smith, JA Green (2015)
Placental PAGs: gene origins, expression patterns, and use as markers of pregnancyReproduction, 149
AL Hughes, JA Green, H Piontkivska, RM Roberts (2003)
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M Majewska, A Lipka, L Paukszto, JP Jastrzebski, K Myszczynski, M Gowkielewicz, M Jozwik, MK Majewski (2017)
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BP Telugu, AM Walker, JA Green (2009)
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Mitochondrial genomes reveal slow rates of molecular evolution and the timing of speciation in beavers (Castor), one of the largest rodent speciesPLoS One, 1
The pregnancy-associated glycoprotein-like family (PAG-L) is a large group of chorionic products, expressed in the pre-placental trophoblast and later in the post-implantational chorionic epithelium, and are involved in proper placenta development and embryo-maternal interaction in eutherians. This study describes identification of the PAG-L family in the genome of the Eurasian beaver (Castor fiber L.), named CfPAG-L. We identified 7657 bp of the CfPAG-L gDNA sequence (Acc. No. KX377932), encompassing nine exons (1–9) and eight introns (A–H). The length of the CfPAG-L exons (59–200 bp) was equivalently similar to the only known counterparts of bPAG1, bPAG2, and pPAG2. The length of the CfPAG-L introns ranged 288–1937 bp and was completely different from previously known PAG introns. The exonic CfPAG-L regions revealed 50.3–72.9% homology with equivalent segments of bPAG1 and pPAG2 structure. The intronic CfPAG-L regions alignments revealed a lack of homology. Within the entire CfPAG-L gene, 31 potential single nucleotide variants (SNV: 7 transversions and 24 transitions) were predicted. The identified exonic polymorphic loci did not affect the amino acid sequence of the CfPAG-L polypeptide precursor. This is the first report describing the CfPAG-L gene sequence, structural organization, and SNVs in the Eurasian beaver, one of the largest rodents.
Functional & Integrative Genomics – Springer Journals
Published: Mar 29, 2017
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