Mammalian Genome 9, 915–917 (1998). Incorporating Mouse Genome © Springer-Verlag New York Inc. 1998 1 2 1 1 1 Takahiro Ito, Michael F. Seldin, Makoto M. Taketo, Takeo Kubo, Shunji Natori Graduate School of Pharmaceutical Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan Rowe Program in Genetics, Department of Biological Chemistry, University of California, Davis, California 95616, USA Received: 4 June 1998 / Accepted: 23 July 1998 Transcription elongation factor S-II was originally purified as a SII-T1 genes (Park et al. 1994; Weaver and Kane 1997), but stimulatory protein of RNA polymerase II from mouse Ehrlich was almost the same as that of the Xenopus general S-II gene ascites tumor cells (Sekimizu et al. 1976; see Natori 1982 for xTFIIS.oA (Plant et al. 1996; Fig. 1B). The Xenopus general S-II review), and many S-II cDNA clones have been isolated from gene consists of ten exons, including unusual exon6/intron6/exon7 various organisms (Hirashima et al. 1988; Marshall et al. 1990; junction structures found in the mouse SII-T1 gene. The human Nakanishi et al. 1992; Chen et al. 1992). S-II has been demon- general S-II gene (TCEA1) was found to be intronless, whereas the strated to enable RNA polymerase II to read-through
Mammalian Genome – Springer Journals
Published: Nov 1, 1998
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