Gene CG17604 of Drosophila melanogaster May Be a Functional Homolog of Yeast Gene ZIP1 and Mammal Gene SCP1 (SYCP1) Encoding Proteins of the Synaptonemal Complex

Gene CG17604 of Drosophila melanogaster May Be a Functional Homolog of Yeast Gene ZIP1 and Mammal... From data on the molecular organization of transverse filament proteins of the synaptonemal complex (SC)—Zip1 in yeast and SCP1 in mammals—and on the width of the SC central space in these organisms and in Drosophila, the putative molecular structure and size of a transverse filament protein of the SC in Drosophila has been inferred. Using genetic and molecular databases and software from the Internet, we carried out in silico screening for a candidate gene for the Drosophila transverse filament protein. As a most likely candidate, gene c(3)G was chosen. The search in the 250-kb region overlapping the locus of this gene (sections 88E-89B) and containing 78 predicted genes has revealed only one gene,CG17604, whose protein meets all requirements for the transverse filament protein of the SC. It was suggested that gene CG17604is gene c(3)G. In this case, genec(3)G must be localized in section 89A7-8 of the cytological map of Drosophila melanogaster. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Gene CG17604 of Drosophila melanogaster May Be a Functional Homolog of Yeast Gene ZIP1 and Mammal Gene SCP1 (SYCP1) Encoding Proteins of the Synaptonemal Complex

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Publisher
Kluwer Academic Publishers-Plenum Publishers
Copyright
Copyright © 2002 by MAIK “Nauka/Interperiodica”
Subject
Biomedicine; Human Genetics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1023/A:1013728214562
Publisher site
See Article on Publisher Site

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