GC–MS study of thermochemical conversion of guaifenesin in the presence of 1-butyl-3-methylimidazolium-based ionic liquids

GC–MS study of thermochemical conversion of guaifenesin in the presence of... Thermochemical conversion of guaifenesin was performed in the presence of 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM][BF4] ionic liquid at 80 °C within 2 h. After evaluating the effect of different parameters, such as protic and nonprotic solvents, temperature, reaction time, 1-butyl-3-methylimidazolium-based ionic liquids as process media, and the amount of ionic liquid, the results demonstrate that [BMIM][BF4] facilitates the conversion of guaifenesin to 3-(2-methoxyphenoxy)propanal and other novel products, while [BMIM]Cl favors C–O bond cleavage to 2-methoxyphenol (guaiacol). The ionic liquid [BMIM][BF4] was used three times without any loss of catalytic activity. Gas chromatography–mass spectrometry (GC–MS) experiments were performed in this study to reveal the guaifenesin degradation and product formation characteristics. According to the distribution of the guaifenesin conversion products, the most plausible mechanisms were proposed by using GC–MS data. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

GC–MS study of thermochemical conversion of guaifenesin in the presence of 1-butyl-3-methylimidazolium-based ionic liquids

Loading next page...
 
/lp/springer_journal/gc-ms-study-of-thermochemical-conversion-of-guaifenesin-in-the-q3hJidv4Kb
Publisher
Springer Netherlands
Copyright
Copyright © 2017 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-016-2858-3
Publisher site
See Article on Publisher Site

Abstract

Thermochemical conversion of guaifenesin was performed in the presence of 1-butyl-3-methylimidazolium tetrafluoroborate [BMIM][BF4] ionic liquid at 80 °C within 2 h. After evaluating the effect of different parameters, such as protic and nonprotic solvents, temperature, reaction time, 1-butyl-3-methylimidazolium-based ionic liquids as process media, and the amount of ionic liquid, the results demonstrate that [BMIM][BF4] facilitates the conversion of guaifenesin to 3-(2-methoxyphenoxy)propanal and other novel products, while [BMIM]Cl favors C–O bond cleavage to 2-methoxyphenol (guaiacol). The ionic liquid [BMIM][BF4] was used three times without any loss of catalytic activity. Gas chromatography–mass spectrometry (GC–MS) experiments were performed in this study to reveal the guaifenesin degradation and product formation characteristics. According to the distribution of the guaifenesin conversion products, the most plausible mechanisms were proposed by using GC–MS data.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Jan 11, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve Freelancer

DeepDyve Pro

Price
FREE
$49/month

$360/year
Save searches from
Google Scholar,
PubMed
Create lists to
organize your research
Export lists, citations
Read DeepDyve articles
Abstract access only
Unlimited access to over
18 million full-text articles
Print
20 pages/month
PDF Discount
20% off