Functions of transcription factor TRF2 Drosophila melanogaster

Functions of transcription factor TRF2 Drosophila melanogaster A study was made of the function of the Drosophila melanogaster TRF2 protein. Expression analysis of the trf2 P1 mutation implicated TRF2 in the D. melanogaster embryo development. High-level expression of the trf2 gene was observed in female germline cells. A high level of TRF2 was detected in primary spermatocytes and trophocytes, characterized by intense transcription. In the female gonads, TRF2 was detected in both nurse cells with intense transcription and transcriptionally inactive oocyte nuclei. In addition, TRF2 proved to be necessary for premeiotic chromatin condensation and further differentiation of germline cells. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Functions of transcription factor TRF2 Drosophila melanogaster

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Publisher
Springer Journals
Copyright
Copyright © 2008 by Pleiades Publishing, Ltd.
Subject
Biomedicine; Microbial Genetics and Genomics; Animal Genetics and Genomics; Human Genetics
ISSN
1022-7954
eISSN
1608-3369
D.O.I.
10.1134/S1022795408030034
Publisher site
See Article on Publisher Site

Abstract

A study was made of the function of the Drosophila melanogaster TRF2 protein. Expression analysis of the trf2 P1 mutation implicated TRF2 in the D. melanogaster embryo development. High-level expression of the trf2 gene was observed in female germline cells. A high level of TRF2 was detected in primary spermatocytes and trophocytes, characterized by intense transcription. In the female gonads, TRF2 was detected in both nurse cells with intense transcription and transcriptionally inactive oocyte nuclei. In addition, TRF2 proved to be necessary for premeiotic chromatin condensation and further differentiation of germline cells.

Journal

Russian Journal of GeneticsSpringer Journals

Published: Jan 19, 2011

References

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