Ann Hematol (2017) 96:1763–1765 DOI 10.1007/s00277-017-3089-4 LETTER TO THE EDITOR Frequency of hemoglobin E/β-thalassemia compound heterozygotes with low hemoglobin F phenotype among cases with a diagnosis of hemoglobin E homozygote, determined by high-performance liquid chromatography, in prenatal control program for β-thalassemia 1 1 1 1 Peerapon Wong & Arunee Srichaiya & Pawanrat Suannum & Prissana Charoenporn & 1 1 1 Sawichayaporn Jermnim & Monthira Chan-In & Akamon Tapprom & Rawisut Deoisares Received: 17 July 2017 /Accepted: 1 August 2017 /Published online: 12 August 2017 # Springer-Verlag GmbH Germany 2017 Dear Editor, Our study was conducted prospectively in prenatal control program for β-thalassemia in the lower north Hemoglobin (Hb) E (HBB:c.79G>A)/β-thalassemia of Thailand, between February 2014 and May 2017. disease is the most common thalassemia syndrome in All couples with a phenotypic diagnosis of homozygous Southeast Asian countries with a high prevalence of Hb E by high-performance liquid chromatography Hb E. Even though patients could present with a wide (HPLC: VARIANT™) in one person, and heterozygous spectrum of clinical severity, the disease accounts for or homozygous Hb E in the other, were recruited. half of the severe β-thalassemia patients worldwide . Phenotypic diagnosis of Hb E homozygote comprised Among individuals
Annals of Hematology – Springer Journals
Published: Aug 12, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera