Osteoporos Int (2017) 28:2557–2564 DOI 10.1007/s00198-017-4091-3 ORIGINAL ARTICLE FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry 1 2 3 1 4 W. D. Leslie & S. R. Majumdar & S. N. Morin & L. M. Lix & H. Johansson & 4 4 4,5 A. Oden & E. V. McCloskey & J. A. Kanis Received: 3 April 2017 /Accepted: 14 May 2017 /Published online: 7 June 2017 International Osteoporosis Foundation and National Osteoporosis Foundation 2017 Abstract and observed cumulative fracture probability. The gradient of Summary In a large clinical registry for the province of risk for FRAX probability and incident fracture was examined Manitoba, Canada, FRAX predicted incident MOF and hip frac- overall and for 5-year intervals. ture from 1 to 15 years following baseline assessment. A simple Results FRAX predicted incident MOF and hip fracture for all linear rescaling of FRAX outputs seems useful for predicting time intervals. There was no attenuation in the gradient of risk both short- and long-term fracture risk in this population. for MOF even for years >10. Gradient of risk was slightly Introduction FRAX® estimates 10-year probability of major lower for hip fracture prediction in years >10 vs
Osteoporosis International – Springer Journals
Published: Jun 7, 2017
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