FRAX for fracture prediction shorter and longer than 10years: the Manitoba BMD registry

FRAX for fracture prediction shorter and longer than 10years: the Manitoba BMD registry Osteoporos Int (2017) 28:2557–2564 DOI 10.1007/s00198-017-4091-3 ORIGINAL ARTICLE FRAX for fracture prediction shorter and longer than 10 years: the Manitoba BMD registry 1 2 3 1 4 W. D. Leslie & S. R. Majumdar & S. N. Morin & L. M. Lix & H. Johansson & 4 4 4,5 A. Oden & E. V. McCloskey & J. A. Kanis Received: 3 April 2017 /Accepted: 14 May 2017 /Published online: 7 June 2017 International Osteoporosis Foundation and National Osteoporosis Foundation 2017 Abstract and observed cumulative fracture probability. The gradient of Summary In a large clinical registry for the province of risk for FRAX probability and incident fracture was examined Manitoba, Canada, FRAX predicted incident MOF and hip frac- overall and for 5-year intervals. ture from 1 to 15 years following baseline assessment. A simple Results FRAX predicted incident MOF and hip fracture for all linear rescaling of FRAX outputs seems useful for predicting time intervals. There was no attenuation in the gradient of risk both short- and long-term fracture risk in this population. for MOF even for years >10. Gradient of risk was slightly Introduction FRAX® estimates 10-year probability of major lower for hip fracture prediction in years >10 vs http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Osteoporosis International Springer Journals

FRAX for fracture prediction shorter and longer than 10years: the Manitoba BMD registry

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Publisher
Springer London
Copyright
Copyright © 2017 by International Osteoporosis Foundation and National Osteoporosis Foundation
Subject
Medicine & Public Health; Orthopedics; Endocrinology; Rheumatology
ISSN
0937-941X
eISSN
1433-2965
D.O.I.
10.1007/s00198-017-4091-3
Publisher site
See Article on Publisher Site

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