Access the full text.
Sign up today, get DeepDyve free for 14 days.
LP Fried, CM Tangen, J Walston, AB Newman, C Hirsch, J Gottdiener, T Seeman, R Tracy, WJ Kop, G Burke, MA McBurnie (2001)
Frailty in older adults: evidence for a phenotypeJ Gerontol A Biol Sci Med Sci, 56
D Gnjidic, SN Hilmer, FM Blyth, V Naganathan, RG Cumming, DJ Handelsman, AJ McLachlan, DR Abernethy, E Banks, DG Couteur (2012)
High-risk prescribing and incidence of frailty among older community-dwelling menClin Pharmacol Ther, 91
R Wang, L Chen, L Fan, D Gao, Z Liang, J He, W Gong, L Gao (2015)
Incidence and effects of polypharmacy on clinical outcome among patients aged 80+: a five-year follow-up studyPLoS One, 10
TR Fried, J O'Leary, V Towle, MK Goldstein, M Trentalange, DK Martin (2014)
Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic reviewJ Am Geriatr Soc, 62
SW Lai, KF Liao, CC Liao, CH Muo, CS Liu, FC Sung (2010)
Polypharmacy correlates with increased risk for hip fracture in the elderly: a population-based studyMedicine, 89
JE Morley, B Vellas, GA Kan, SD Anker, JM Bauer, R Bernabei, M Cesari, WC Chumlea, W Doehner, J Evans, LP Fried, JM Guralnik, PR Katz, TK Malmstrom, RJ McCarter, LM Gutierrez Robledo, K Rockwood, S Haehling, MF Vandewoude, J Walston (2013)
Frailty consensus: a call to actionJ Am Med Dir Assoc, 14
SC Frazier (2005)
Health outcomes and polypharmacy in elderly individuals: an integrated literature reviewJ Gerontol Nurs, 31
D Gnjidic, SN Hilmer (2012)
Potential contribution of medications to frailtyJ Am Geriatr Soc, 60
C Beer, Z Hyde, OP Almeida, P Norman, GJ Hankey, BB Yeap, L Flicker (2011)
Quality use of medicines and health outcomes among a cohort of community dwelling older men: an observational studyBr J Clin Pharmacol, 71
M Herr, JM Robine, J Pinot, JJ Arvieu, J Ankri (2015)
Polypharmacy and frailty: prevalence, relationship, and impact on mortality in a French sample of 2350 old peoplePharmacoepidemiol Drug Saf, 24
P Gerretsen, BG Pollock (2011)
Drugs with anticholinergic properties: a current perspective on use and safetyExpert Opin Drug Saf, 10
T Shamliyan, KM Talley, R Ramakrishnan, RL Kane (2013)
Association of frailty with survival: a systematic literature reviewAgeing Res Rev, 12
CF Dormann, J Elith, S Bacher, C Buchmann, G Carl, G Carre, JRG Marquez, B Gruber, B Lafourcade, PJ Leitao, T Munkemuller, C McClean, PE Osborne, B Reineking, B Schroder, AK Skidmore, D Zurell, S Lautenbach (2013)
Collinearity: a review of methods to deal with it and a simulation study evaluating their performanceEcography, 36
MH Beers, JG Ouslander, SF Fingold, H Morgenstern, DB Reuben, W Rogers, MJ Zeffren, JC Beck (1992)
Inappropriate medication prescribing in skilled-nursing facilitiesAnn Intern Med, 117
F Moulis, G Moulis, L Balardy, S Gerard, F Montastruc, S Sourdet, ME Rouge-Bugat, M Lapeyre-Mestre, JL Montastruc, Y Rolland, B Vellas (2015)
Exposure to atropinic drugs and frailty statusJ Am Med Dir Assoc, 16
D Gnjidic, SN Hilmer, FM Blyth, V Naganathan, L Waite, MJ Seibel, AJ McLachlan, RG Cumming, DJ Handelsman, DG Couteur (2012)
Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomesJ Clin Epidemiol, 65
M Jardin, A Bocquier, S Cortaredona, S Nauleau, C Millon, S Savard-Chambard, V Allaria-Lapierre, V Sciortino, G Bouvenot, P Verger (2012)
Potentially inappropriate prescriptions for the elderly: a study of health insurance reimbursements in southeastern FranceRevue d'epidemiologie et de sante publique, 60
E Tommelein, E Mehuys, M Petrovic, A Somers, P Colin, K Boussery (2015)
Potentially inappropriate prescribing in community-dwelling older people across Europe: a systematic literature reviewEur J Clin Pharmacol, 71
ML Laroche, JP Charmes, L Merle (2007)
Potentially inappropriate medications in the elderly: a French consensus panel listEur J Clin Pharmacol, 63
H Bergman, L Ferrucci, J Guralnik, DB Hogan, S Hummel, S Karunananthan, C Wolfson (2007)
Frailty: an emerging research and clinical paradigm--issues and controversiesJ Gerontol A Biol Sci Med Sci, 62
CI Chang, DC Chan, KN Kuo, CA Hsiung, CY Chen (2011)
Prevalence and correlates of geriatric frailty in a northern Taiwan communityJ Formos Med Assoc, 110
KU Saum, B Schottker, AD Meid, B Holleczek, WE Haefeli, K Hauer, H Brenner (2017)
Is polypharmacy associated with frailty in older people? Results from the ESTHER cohort studyJ Am Geriatr Soc, 65
Eur J Clin Pharmacol (2017) 73:1165–1172 DOI 10.1007/s00228-017-2276-5 PHARMACOEPIDEMIOLOGY AND PRESCRIPTION Frailty, polypharmacy, and potentially inappropriate medications in old people: findings in a representative sample of the French population 1,2 3,4 1 3 Marie Herr & Nicolas Sirven & Hélène Grondin & Sylvain Pichetti & Catherine Sermet Received: 28 February 2017 /Accepted: 31 May 2017 /Published online: 11 June 2017 Springer-Verlag GmbH Germany 2017 Abstract The analyses used Poisson regression models, with the num- Purpose This study analyses the relationship between medi- ber of frailty criteria as dependent variable. cation use and frailty by considering the quantity of medica- Results The study population was composed of 1003 women tions prescribed (polypharmacy) and the quality of medication and 887 men, of mean age 74.7 +/− 7.4 years. Polypharmacy prescribing (according to French criteria for Potentially (5 to 9 drugs) and excessive polypharmacy (≥10 drugs) were Inappropriate Medications—PIMs) in people aged 65 and reported in 42.9 and 27.4% of the study population, respec- over. tively, while 46.7% of the study population received at least Methods This is a cross-sectional study based on the data one PIM during the year 2012. Polypharmacy and PIMs were from a nationally representative study about health
European Journal of Clinical Pharmacology – Springer Journals
Published: Jun 11, 2017
Access the full text.
Sign up today, get DeepDyve free for 14 days.