Eur J Clin Pharmacol (2017) 73:1165–1172 DOI 10.1007/s00228-017-2276-5 PHARMACOEPIDEMIOLOGY AND PRESCRIPTION Frailty, polypharmacy, and potentially inappropriate medications in old people: findings in a representative sample of the French population 1,2 3,4 1 3 Marie Herr & Nicolas Sirven & Hélène Grondin & Sylvain Pichetti & Catherine Sermet Received: 28 February 2017 /Accepted: 31 May 2017 /Published online: 11 June 2017 Springer-Verlag GmbH Germany 2017 Abstract The analyses used Poisson regression models, with the num- Purpose This study analyses the relationship between medi- ber of frailty criteria as dependent variable. cation use and frailty by considering the quantity of medica- Results The study population was composed of 1003 women tions prescribed (polypharmacy) and the quality of medication and 887 men, of mean age 74.7 +/− 7.4 years. Polypharmacy prescribing (according to French criteria for Potentially (5 to 9 drugs) and excessive polypharmacy (≥10 drugs) were Inappropriate Medications—PIMs) in people aged 65 and reported in 42.9 and 27.4% of the study population, respec- over. tively, while 46.7% of the study population received at least Methods This is a cross-sectional study based on the data one PIM during the year 2012. Polypharmacy and PIMs were from a nationally representative study about health
European Journal of Clinical Pharmacology – Springer Journals
Published: Jun 11, 2017
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