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R. Penagini, R. Sweis, A. Mauro, G. Domingues, A. Vales, D. Sifrim (2015)
Inconsistency in the Diagnosis of Functional Heartburn: Usefulness of Prolonged Wireless pH Monitoring in Patients With Proton Pump Inhibitor Refractory Gastroesophageal Reflux DiseaseJournal of Neurogastroenterology and Motility, 21
P. Kahrilas, N. Shaheen, M. Vaezi, S. Hiltz, Edgar Black, I. Modlin, Steve Johnson, John Allen, J. Brill (2008)
American Gastroenterological Association Medical Position Statement on the management of gastroesophageal reflux disease.Gastroenterology, 135 4
A. Akhmanova, A. Yap (2008)
Organizing Junctions at the Cell-Cell InterfaceCell, 135
C. Calabrese, A. Fabbri, M. Bortolotti, G. Cenacchi, A. Areni, C. Scialpi, M. Miglioli, G. Febo (2003)
Dilated intercellular spaces as a marker of oesophageal damage: comparative results in gastro‐oesophageal reflux disease with or without bile refluxAlimentary Pharmacology & Therapeutics, 18
N. Bortoli, I. Martinucci, E. Savarino, M. Bellini, A. Bredenoord, R. Franchi, L. Bertani, M. Furnari, V. Savarino, C. Blandizzi, S. Marchi (2014)
Proton pump inhibitor responders who are not confirmed as GERD patients with impedance and pH monitoring: who are they?Neurogastroenterology & Motility, 26
T. Runge, N. Shaheen, Z. Djukic, Suzanne Hallquist, R. Orlando (2016)
Cleavage of E-Cadherin Contributes to Defective Barrier Function in Neosquamous EpitheliumDigestive Diseases and Sciences, 61
N. Tobey, J. Carson, R. Alkiek, R. Orlando (1996)
Dilated intercellular spaces: a morphological feature of acid reflux--damaged human esophageal epithelium.Gastroenterology, 111 5
Amit Patel, G. Sayuk, C. Gyawali (2015)
Parameters on esophageal pH-impedance monitoring that predict outcomes of patients with gastroesophageal reflux disease.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 13 5
R. Caviglia, M. Ribolsi, N. Maggiano, A. Gabbrielli, S. Emerenziani, M. Guarino, S. Carotti, F. Habib, C. Rabitti, M. Cicala (2005)
Dilated Intercellular Spaces of Esophageal Epithelium in Nonerosive Reflux Disease Patients with Physiological Esophageal Acid ExposureThe American Journal of Gastroenterology, 100
H. El‐Serag, N. Petersen, J. Carter, D. Graham, Peter Richardson, R. Genta, L. Rabeneck (2004)
Gastroesophageal reflux among different racial groups in the United States.Gastroenterology, 126 7
C. Calabrese, M. Bortolotti, A. Fabbri, A. Areni, G. Cenacchi, C. Scialpi, M. Miglioli, G. Febo (2005)
Reversibility of GERD Ultrastructural Alterations and Relief of Symptoms After Omeprazole TreatmentThe American Journal of Gastroenterology, 100
W. Barlow, R. Orlando (2005)
The pathogenesis of heartburn in nonerosive reflux disease: a unifying hypothesis.Gastroenterology, 128 3
N. Tobey, C. Argote, S. Hosseini, Roy Orlando (2004)
Calcium-switch technique and junctional permeability in native rabbit esophageal epithelium.American journal of physiology. Gastrointestinal and liver physiology, 286 6
G. Locke, N. Talley, S. Fett, A. Zinsmeister, L. Melton (1997)
Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota.Gastroenterology, 112 5
B. Jovov, J. Que, N. Tobey, Z. Djukic, B. Hogan, R. Orlando (2011)
Role of E-cadherin in the Pathogenesis of Gastroesophageal Reflux DiseaseThe American Journal of Gastroenterology, 106
Andrea Hartsock, W. Nelson (2008)
Adherens and tight junctions: structure, function and connections to the actin cytoskeleton.Biochimica et biophysica acta, 1778 3
N. Tobey, S. Hosseini, C. Argote, A.M. Dobrucali, M. Awayda, RC Orlando (2004)
Dilated Intercellular Spaces and Shunt Permeability in Nonerosive Acid-Damaged Esophageal EpitheliumAmerican Journal of Gastroenterology, 99
H. El‐Serag, Stephen Sweet, C. Winchester, J. Dent (2013)
Update on the epidemiology of gastro-oesophageal reflux disease: a systematic reviewGut, 63
M. Vaezi, Yu-Xiao Yang, C. Howden (2017)
Complications of Proton Pump Inhibitor Therapy.Gastroenterology, 153 1
Dig Dis Sci (2018) 63:628–635 https://doi.org/10.1007/s10620-017-4815-4 ORIGINAL ARTICLE Fragments of e-Cadherin as Biomarkers of Non-erosive Reflux Disease 1,3 1,2 1,5 1,8 • • • • Biljana Jovov Craig C. Reed Nicholas J. Shaheen Amy Pruitt 1,6 1,7 1,4 1,7 • • • Kathleen Ferrell Geraldine S. Orlando Zorka Djukic Roy C. Orlando Received: 26 August 2017 / Accepted: 17 October 2017 / Published online: 25 October 2017 Springer Science+Business Media, LLC 2017 Abstract received dexlansoprazole 30 mg daily for 4 weeks, and Background Approximately, 20% of patients with heart- heartburn was assessed by daily diary entry. Post-treatment burn and normal endoscopic findings do not symptomati- blood samples were obtained for serum NTFs. A control cally improve on proton pump inhibitor (PPI) therapy group without GERD symptoms (n = 6) had biopsies for making diagnosis and treatment uncertain. A biomarker CTFs and a second control group (n = 20) blood serum for distinguishing PPI-responsive from PPI-refractory heart- serum NTFs. burn is desirable. Results Twenty-seven of 29 patients (93.1%) with endo- Aims We performed a pilot study assessing whether car- scopy-negative heartburn, but 0 of 6 controls, were positive boxy(C)-terminal fragments (CTFs) of e-cadherin in eso- for CTFs. All patients and
Digestive Diseases and Sciences – Springer Journals
Published: Oct 25, 2017
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