J. Membrane Biol. 205, 113–114 (2005) DOI: 10.1007/s00232-005-0775-2 Thematic Issue: Ion Channels and Cancer K. Kunzelmann, Guest Editor K. Kunzelmann Institut fu¨ r Physiologie, Universita¨ t Regensburg, Universita¨ tsstraße 31, D-93053 Regensburg, Germany Received: 9 September 2005 Introduction ion channels, such as voltage-gated K channels, promote proliferation of non-excitable epithelial cells Almost ten years ago, Wonderlin and Strobel sum- and support cancer growth. It will be interesting to marized in their excellent topical review in the Jour- learn in the second paper about the role of the nal of Membrane Biology the role of potassium N-methyl-D-aspartate (NMDA) receptor in human channels in proliferation and G1 progression. Since prostate cancer. Abdul and Hoosein will report that this illuminating review, there is an ever increasing the NMDA receptor, which is well known for its number of studies reporting the role of a broad contribution to proliferation of neuronal tissue and spectrumof ion channels in proliferation and carci- development of glioma and neuroblastoma, is also nogenesis. This provides suﬃcient reason to devote a expressed in cancer tissues fromprostate, breast and special issue of the Journal of Membrane Biology to colon. Thus, their results demonstrate that yet an- the role of ion channels
The Journal of Membrane Biology – Springer Journals
Published: Jan 1, 2005
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