Food-Dependent Exercise-Induced Anaphylaxis

Food-Dependent Exercise-Induced Anaphylaxis Purpose of review Food-dependent exercise-induced anaphylaxis (FDEIA) is a form of anaphylaxis that occurs associated with exercise, in which symptoms develop by the combination of food ingestion and physical activity. We aimed to review and discuss the main clinical recommendations for management of FDEIA, focusing on individual factors. Recent findings New diagnostic strategies have been developed to optimize the accuracy of provocation challenges, taking in consideration augmenting factors, such as alcohol or non-steroidal anti-inflammatory drugs. However, FDEIA is still insufficiently diagnosed and a high index of clinical suspicion is usually required. Management is complex and based on preventing the reaction and education of the patient, followed by treatment of the acute episode. Several pharmacological strategies for prophylactic treatment have been proposed; however, they are based mainly in low quality of evidence. Summary For management of FDEIA, the culprit food allergen should be avoided at least 4 h before exercise and the individual needs to be educated on how to practice exercise in safe conditions, particularly recognizing the importance of stopping exercise or physical activity at the earliest manifestation of symptoms. This prevention strategy should be developed accordingly to the specific characteristics of the individual and food allergen involved. Due http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Treatment Options in Allergy Springer Journals

Food-Dependent Exercise-Induced Anaphylaxis

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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Allergology; General Practice / Family Medicine
eISSN
2196-3053
D.O.I.
10.1007/s40521-018-0171-7
Publisher site
See Article on Publisher Site

Abstract

Purpose of review Food-dependent exercise-induced anaphylaxis (FDEIA) is a form of anaphylaxis that occurs associated with exercise, in which symptoms develop by the combination of food ingestion and physical activity. We aimed to review and discuss the main clinical recommendations for management of FDEIA, focusing on individual factors. Recent findings New diagnostic strategies have been developed to optimize the accuracy of provocation challenges, taking in consideration augmenting factors, such as alcohol or non-steroidal anti-inflammatory drugs. However, FDEIA is still insufficiently diagnosed and a high index of clinical suspicion is usually required. Management is complex and based on preventing the reaction and education of the patient, followed by treatment of the acute episode. Several pharmacological strategies for prophylactic treatment have been proposed; however, they are based mainly in low quality of evidence. Summary For management of FDEIA, the culprit food allergen should be avoided at least 4 h before exercise and the individual needs to be educated on how to practice exercise in safe conditions, particularly recognizing the importance of stopping exercise or physical activity at the earliest manifestation of symptoms. This prevention strategy should be developed accordingly to the specific characteristics of the individual and food allergen involved. Due

Journal

Current Treatment Options in AllergySpringer Journals

Published: May 22, 2018

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