Access the full text.
Sign up today, get DeepDyve free for 14 days.
R. Bizzarri, M. Serresi, S. Luin, F. Beltram (2009)
Green fluorescent protein based pH indicators for in vivo use: a reviewAnalytical and Bioanalytical Chemistry, 393
Li-Yi Chen, Chia‐wei Wang, Zhiqin Yuan, Huan‐Tsung Chang (2015)
Fluorescent gold nanoclusters: recent advances in sensing and imaging.Analytical chemistry, 87 1
Dongil Lee, R. Donkers, Gangli Wang, A. Harper, R. Murray (2004)
Electrochemistry and optical absorbance and luminescence of molecule-like Au38 nanoparticles.Journal of the American Chemical Society, 126 19
Y. Negishi, K. Nobusada, T. Tsukuda (2005)
Glutathione-protected gold clusters revisited: bridging the gap between gold(I)-thiolate complexes and thiolate-protected gold nanocrystals.Journal of the American Chemical Society, 127 14
Heng-Chia Chang, J. Ho (2015)
Gold Nanocluster-Assisted Fluorescent Detection for Hydrogen Peroxide and Cholesterol Based on the Inner Filter Effect of Gold Nanoparticles.Analytical chemistry, 87 20
Xue-liang Wang, Jie Yang, K. Jiao (2008)
Electrochemical Study on the Interaction of Protein with Bromothymol Blue and Its Analytical ApplicationChemical Research in Chinese Universities, 24
D. Knopp, D. Tang, R. Niessner (2009)
Review: bioanalytical applications of biomolecule-functionalized nanometer-sized doped silica particles.Analytica chimica acta, 647 1
K. Male, B. Lachance, S. Hrapovic, G. Sunahara, J. Luong (2008)
Assessment of cytotoxicity of quantum dots and gold nanoparticles using cell-based impedance spectroscopy.Analytical chemistry, 80 14
Y. Cheng-nong (2010)
Study on the interaction of bromothymol blue and bovine serum albuminChemical Research and Application
Li-ning Sun, Hongshang Peng, Matthias Stich, D. Achatz, O. Wolfbeis (2009)
pH sensor based on upconverting luminescent lanthanide nanorods.Chemical communications, 33
N. Hsu, Yang-Wei Lin (2016)
Microwave-assisted synthesis of bovine serum albumin–gold nanoclusters and their fluorescence-quenched sensing of Hg2+ ionsNew Journal of Chemistry, 40
Dhritiman Chakraborty, Gopika Rajan, R. Isaac (2015)
A Splendid Blend of Nanotechnology and Forensic ScienceJournal of Nanotechnology in Engineering and Medicine, 6
Reham Ali, Sayed Saleh, R. Meier, H. Azab, Ibraheim Abdelgawad, O. Wolfbeis (2010)
Upconverting nanoparticle based optical sensor for carbon dioxideSensors and Actuators B-chemical, 150
Changqin Ding, Yang Tian (2015)
Gold nanocluster-based fluorescence biosensor for targeted imaging in cancer cells and ratiometric determination of intracellular pH.Biosensors & bioelectronics, 65
A. Donaldson, I. Lamont (2013)
Biochemistry Changes That Occur after Death: Potential Markers for Determining Post-Mortem IntervalPLoS ONE, 8
D. Baumann, D. Hofmann, S. Nullmeier, P. Panther, C. Dietze, A. Musyanovych, Sandra Ritz, K. Landfester, V. Mailänder (2013)
Complex encounters: nanoparticles in whole blood and their uptake into different types of white blood cells.Nanomedicine, 8 5
Haohua Deng, Gang-Wei Wu, Zhi-Qiang Zou, Huaping Peng, Ailin Liu, Xinhua Lin, X. Xia, Wei Chen (2015)
pH-Sensitive gold nanoclusters: preparation and analytical applications for urea, urease, and urease inhibitor detection.Chemical communications, 51 37
L. Putney, D. Barber (2003)
Na-H Exchange-dependent Increase in Intracellular pH Times G2/M Entry and Transition*Journal of Biological Chemistry, 278
J. Lin, Chih-Hsien Lee, Jyun-tai Hsieh, Hsueh-Hsiao Wang, J. Li, Ji‐Lin Shen, W. Chan, H. Yeh, Walter Chang (2009)
Synthesis of Fluorescent Metallic Nanoclusters toward Biomedical Application: Recent Progress and Present Challenges
I. Madshus (1988)
Regulation of intracellular pH in eukaryotic cells.The Biochemical journal, 250 1
Jianping Xie, Yuangang Zheng, J. Ying (2010)
Highly selective and ultrasensitive detection of Hg(2+) based on fluorescence quenching of Au nanoclusters by Hg(2+)-Au(+) interactions.Chemical communications, 46 6
Stephan Hesse, G. Ruijter, C. Dijkema, Jaap Visser (2000)
Measurement of intracellular (compartmental) pH by 31P NMR in Aspergillus niger.Journal of biotechnology, 77 1
Xianfeng Zhou, F. Su, Hongguang Lu, Patti Senechal-Willis, Yanqing Tian, Roger Johnson, D. Meldrum (2012)
An FRET-based ratiometric chemosensor for in vitro cellular fluorescence analyses of pH.Biomaterials, 33 1
N. Hsu, Yangming Lin (2015)
Microwave-Assisted Synthesis of Bovine Serum Albumin-Gold Nanoclusters and Their Fluorescence-Quenched Sensing of Hg 2 + ions
Mehdi Damaghi, Jonathan Wojtkowiak, R. Gillies (2013)
pH sensing and regulation in cancerFrontiers in Physiology, 4
Venkatesh Saligrama (2008)
Deterministic Designs with Deterministic Guarantees: Toeplitz Compressed Sensing Matrices, Sequence Designs and System IdentificationArXiv, abs/0806.4958
Yinhui Li, Yijun Wang, Sheng Yang, Yirong Zhao, Lin Yuan, Jing Zheng, Ronghua Yang (2015)
Hemicyanine-based high resolution ratiometric near-infrared fluorescent probe for monitoring pH changes in vivo.Analytical chemistry, 87 4
E. Vidal, M. Palomeque, A. Lista, Beatriz Fernández Band (2003)
Flow injection analysis: Rayleigh light scattering technique for total protein determinationAnalytical and Bioanalytical Chemistry, 376
G. Small (1992)
Spectrometric Identification of Organic CompoundsVibrational Spectroscopy, 4
Min Wang, Qingsong Mei, Kui Zhang, Zhongpin Zhang (2012)
Protein-gold nanoclusters for identification of amino acids by metal ions modulated ratiometric fluorescence.The Analyst, 137 7
Yaolin Xu, J. Sherwood, Ying Qin, Dorothy Crowley, M. Bonizzoni, Y. Bao (2014)
The role of protein characteristics in the formation and fluorescence of Au nanoclusters.Nanoscale, 6 3
G. Orgován, B. Noszál (2011)
Electrodeless, accurate pH determination in highly basic media using a new set of (1)H NMR pH indicators.Journal of pharmaceutical and biomedical analysis, 54 5
Jianping Xie, Yuangang Zheng, J. Ying (2009)
Protein-directed synthesis of highly fluorescent gold nanoclusters.Journal of the American Chemical Society, 131 3
W. Busa, R. Nuccitelli (1984)
Metabolic regulation via intracellular pH.The American journal of physiology, 246 4 Pt 2
Rumi Khandelia, Satyapriya Bhandari, Uday Pan, S. Ghosh, A. Chattopadhyay (2015)
Gold Nanocluster Embedded Albumin Nanoparticles for Two-Photon Imaging of Cancer Cells Accompanying Drug Delivery.Small, 11 33
A. Donaldson, I. Lamont (2014)
Estimation of post-mortem interval using biochemical markersAustralian Journal of Forensic Sciences, 46
Cheng-An Lin, Ting-Ya Yang, Chih-Hsien Lee, Sherry Huang, R. Sperling, M. Zanella, J. Li, Ji‐Lin Shen, Hsueh-Hsiao Wang, H. Yeh, W. Parak, Walter Chang (2009)
Synthesis, characterization, and bioconjugation of fluorescent gold nanoclusters toward biological labeling applications.ACS nano, 3 2
S. Walenta, Michael Wetterling, M. Lehrke, G. Schwickert, K. Sundfør, E. Rofstad, W. Mueller‐Klieser (2000)
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers.Cancer research, 60 4
The authors describe the use of gold nanoclusters (AuNCs) with a diameter of ~2 nm for fluorescent sensing of pH values in the range from 5 to 9. The AuNCs were synthesized in the presence of bovine serum albumin (BSA) which acts as both a reducing agent and capping agent. The resulting AuNCs were characterized in terms of size and surface chemistry using TEM and FTIR. The BSA-capped AuNCs display red luminescence, with excitation/emission peaks at 470/640 nm, which is strongly modulated by the pH indicator bromothymol blue (BTB). The effect depends mainly on an inner filter effect due to spectral overlap between the absorption BTB and the emission of the AuNCs. The pH nanosensor responds to pH values in the range from 5 to 9 which is the so-called physiological pH range. The method was applied to detect changes in the pH values that occur after the death of red blood cells. Such pH changes are considered as a potential forensic marker for estimating the time passed since death. The results show the BTB-BSA-AuNC system to be capable of detecting respective intracellular pH changes.
Microchimica Acta – Springer Journals
Published: Jun 6, 2017
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.