Short Communications Incorporating Mouse Genome Mammalian Genome 13, 114–116 (2002). © Springer-Verlag New York Inc. 2002 DOI: 10.1007/s00335-001-2107-x Fluctuation in fertility phenotypes of the heterozygous (Om/+) mice owing to background genes 1 2 1 Wei Dong Zhao, Akira Ishikawa, Noboru Wakasugi Laboratory of Animal Reproduction, Division of Applied Genetics and Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan Laboratory of Animal Genetics, Division of Applied Genetics and Physiology, Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa-ku, Nagoya 464-8601, Japan Received: 6 July 2001 / Accepted: 28 September 2001 The Ovum mutant (Om) locus of the mouse constitutes the unidi- or affecting their fertilizing ability in the genetic background of B6 rectional incompatibility system, which is responsible for early and DDK strains. embryonic death (Babinet et al. 1990; Cohen-Tannoudji et al. Fertility phenotypes of the heterozygous (Om/+) females with 1996). For the allele symbols of the Om locus, the allele of DDK different proportion of DDK background genes strain is shown as Om and that of C57BL/6 (B6) strain as + in the present paper. Wakasugi (1974) reported the following two find- Mating experiments were performed with B6 strain and five kinds ings concerning the backcross,
Mammalian Genome – Springer Journals
Published: Feb 15, 2014
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