Mammalian Genome 8,362-364 (1997). 9 Sprlnger-Verlag New York lnc 1997 FISH mapping of three ammonia metabolism genes (Glul, Cpsl, Gludl) in rat, and the chromosomal localization of GLUL in human and Cpsl in mouse K. Helou, 1 A.T. Das, z W.H. Lamers, z J.M.N. Hoovers, 3 C. Szpirer, q J. Szpirer, 4 K. Klinga-Levan, 1 Giiran Levan 1 1Department of Genetics, G6teborg University Medicinareg. 9C, S-413 90 Gtiteborg, Sweden 2Department of Anatomy and Embryology, Academic Medical Center, University of Amsterdam, The Netherlands 3Institute of Human Genetics, Academic Medical Center, University of Amsterdam, The Netherlands 4Department of Molecular Biology, Universit6 Libre de Bruxelles, B-1640 Rhode-St-G6n~se, Belgium Received: 13 November 1996 / Accepted: 24 January 1997 In recent years, the rat genes encoding glutamate dehydrogenase RATMAP database (URL http://ratmap.gen.gu.se/ratmap/WWW (GLUD; Das et al. 1993), glutamine synthetase (glutamate- Nomen/RNOIdiogrRev96new.GIF). For the mapping of rat Gludl, ammonia ligase, GLUL; van de Zande et al. 1990) and carbamoyl- two clones of genomic DNA (pgGDH6d, 6700 bp containing exon phosphate synthetase 1 (CPS; Van den Hoff et al. 1995) have been 1, and pgGDH2u, 5800 bp containing exons 8-12; Das et al. 1993) isolated. These enzymes have important functions in ammonia were used. The results
Mammalian Genome – Springer Journals
Published: Mar 21, 2009
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