Mammalian Genome 9, Brief Data Report Other imprinted genes have been found clustered in chromo- NPY5 gene to FISH mapping of the porcine somal regions that are conserved between mouse and human. By Chromosome 8p11 determining the extent of the syntenic region, it may be possible to identify more imprinted genes that may map to this region in l A. Wraith, 2 D. Larhammar, 2 B.P. mouse and human. Therefore, we mapped Rasgrfl in the BSS- A. Tornsten, Jackson backcross together with other genes located on central Chr Chowdhary' 9 (Fig. 1). We used the Sp4 clone, which contained a paternally 'Department of Animal Breeding and Genetics, Swedish University of methylated Notl site and a novel tandem repeat sequence located Agricultural Sciences, Box 7023, S-750 07 Uppsala, Sweden near a CpG island (H. Shibata, submitted). The repeat (D9Ncvs53) 2Department of Medical Pharmacology, Uppsala University, Uppsala is located approximately 30 kb upstream of the 5' exon of Rasgrfl Biomedical Centre, Box 593, 751 24 Uppsala, Sweden . Similar short tandem repeat sequences have been found asso- ciated with other known imprinted genes in regions of parental- Received: 5 September 1997/Accepted: 11 November 1997 origin specific methylation. The Rasgrfl-repeat is located
Mammalian Genome – Springer Journals
Published: Mar 21, 2009
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