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First trimester pregnancy ultrasound findings as a function of method of conception in an infertile population

First trimester pregnancy ultrasound findings as a function of method of conception in an... Purpose The aim of this study was to determine whether first trimester ultrasound measurements of crown rump length (CRL) and gestational sac diameter (GSD) differ depending on the method of conception among infertile women. Method Infertile women, ages 21–50 years old, who conceived viable, singleton pregnancies via fresh embryo transfer (ET), frozen ET, non-in vitro fertilization (IVF) fertility treatment, or spontaneously were included in this observational cohort study at an academic fertility practice. Embryonic growth trajectories defined by the CRL and GSD at 6 and 8 weeks’ gestation were analyzed and compared among the methods of conception. Results Crown rump length at 6 weeks’ gestation was smaller for conceptions achieved via fresh ET compared with frozen ET in a natural cycle (1.50 vs. 2.50 mm, p = 0.017). Crown rump length was smaller at 8 weeks’ gestation in conceptions achieved via fresh ET compared to frozen ET in a programmed cycle (16.13 vs. 17.02 mm, p =0.039). Conclusion Among infertile women, embryo growth may differ between fresh and frozen ETas early as 6 and 8 weeks’ gestation. . . . . Keywords First trimester Crown rump length Gestational sac diameter Embryo transfer Assisted reproduction Introduction which is in part http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Assisted Reproduction and Genetics Springer Journals

First trimester pregnancy ultrasound findings as a function of method of conception in an infertile population

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Publisher
Springer Journals
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Gynecology; Reproductive Medicine; Human Genetics
ISSN
1058-0468
eISSN
1573-7330
DOI
10.1007/s10815-018-1120-x
pmid
29380277
Publisher site
See Article on Publisher Site

Abstract

Purpose The aim of this study was to determine whether first trimester ultrasound measurements of crown rump length (CRL) and gestational sac diameter (GSD) differ depending on the method of conception among infertile women. Method Infertile women, ages 21–50 years old, who conceived viable, singleton pregnancies via fresh embryo transfer (ET), frozen ET, non-in vitro fertilization (IVF) fertility treatment, or spontaneously were included in this observational cohort study at an academic fertility practice. Embryonic growth trajectories defined by the CRL and GSD at 6 and 8 weeks’ gestation were analyzed and compared among the methods of conception. Results Crown rump length at 6 weeks’ gestation was smaller for conceptions achieved via fresh ET compared with frozen ET in a natural cycle (1.50 vs. 2.50 mm, p = 0.017). Crown rump length was smaller at 8 weeks’ gestation in conceptions achieved via fresh ET compared to frozen ET in a programmed cycle (16.13 vs. 17.02 mm, p =0.039). Conclusion Among infertile women, embryo growth may differ between fresh and frozen ETas early as 6 and 8 weeks’ gestation. . . . . Keywords First trimester Crown rump length Gestational sac diameter Embryo transfer Assisted reproduction Introduction which is in part

Journal

Journal of Assisted Reproduction and GeneticsSpringer Journals

Published: Jan 29, 2018

References