Field outbreak strains of serotype O foot-and-mouth disease virus from India with a deletion in the immunodominant βG-βH loop of the VP1 protein

Field outbreak strains of serotype O foot-and-mouth disease virus from India with a deletion in... Foot-and-mouth disease virus serotype O accounts for around 80 % of the outbreaks in India. Although Indian serotype O isolates belongs to the ME-SA topotype, circulation of different lineages has been noted. After its emergence in the year 2001, the ‘Ind2001’ lineage outcompeted the PanAsia lineage in causing serotype O outbreaks in the year 2009. Three isolates had an amino acid deletion at position 139 in the VP1 coding region and grouped with the ‘Ind2001’ lineage. The currently used Indian vaccine strain of serotype O covers all of the field isolates antigenically. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Field outbreak strains of serotype O foot-and-mouth disease virus from India with a deletion in the immunodominant βG-βH loop of the VP1 protein

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Publisher
Springer Vienna
Copyright
Copyright © 2012 by Springer-Verlag Wien
Subject
Biomedicine; Infectious Diseases; Virology; Medical Microbiology
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-012-1380-1
Publisher site
See Article on Publisher Site

Abstract

Foot-and-mouth disease virus serotype O accounts for around 80 % of the outbreaks in India. Although Indian serotype O isolates belongs to the ME-SA topotype, circulation of different lineages has been noted. After its emergence in the year 2001, the ‘Ind2001’ lineage outcompeted the PanAsia lineage in causing serotype O outbreaks in the year 2009. Three isolates had an amino acid deletion at position 139 in the VP1 coding region and grouped with the ‘Ind2001’ lineage. The currently used Indian vaccine strain of serotype O covers all of the field isolates antigenically.

Journal

Archives of VirologySpringer Journals

Published: Oct 1, 2012

References

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