Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical results

Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical... gmail.com Department of Nuclear Medicine, Background: The performance of a prototype novel digital single-photon emission Chaim Sheba Medical Center, Tel computed tomography (SPECT) camera with multiple pixelated CZT detectors and Hashomer, Ramat Gan, Israel Sackler School of Medicine, Tel high sensitivity collimators (Digital SPECT; Valiance X12 prototype, Molecular Aviv University, Tel Aviv, Israel Dynamics) was evaluated in various clinical settings. Full list of author information is Images obtained in the prototype system were compared to images from an analog available at the end of the article camera fitted with high-resolution collimators. Clinical feasibility, image quality, and diagnostic performance of the prototype were evaluated in 36 SPECT studies in 35 patients including bone (n = 21), brain (n = 5), lung perfusion (n = 3), and parathyroid (n = 3) and one study each of sentinel node and labeled white blood cells. Images were graded on a scale of 1–4 for sharpness, contrast, overall quality, and diagnostic confidence. Results: Digital CZT SPECT provided a statistically significant improvement in sharpness and contrast in clinical cases (mean score of 3.79 ± 0.61 vs. 3.26 ± 0.50 and 3.92 ± 0.29 vs. 3.34 ± 0.47 respectively, p < 0.001 for both). Overall image http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png EJNMMI Physics Springer Journals

Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical results

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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by The Author(s).
Subject
Medicine & Public Health; Nuclear Medicine; Imaging / Radiology; Applied and Technical Physics; Computational Mathematics and Numerical Analysis; Engineering, general
eISSN
2197-7364
D.O.I.
10.1186/s40658-018-0205-z
Publisher site
See Article on Publisher Site

Abstract

gmail.com Department of Nuclear Medicine, Background: The performance of a prototype novel digital single-photon emission Chaim Sheba Medical Center, Tel computed tomography (SPECT) camera with multiple pixelated CZT detectors and Hashomer, Ramat Gan, Israel Sackler School of Medicine, Tel high sensitivity collimators (Digital SPECT; Valiance X12 prototype, Molecular Aviv University, Tel Aviv, Israel Dynamics) was evaluated in various clinical settings. Full list of author information is Images obtained in the prototype system were compared to images from an analog available at the end of the article camera fitted with high-resolution collimators. Clinical feasibility, image quality, and diagnostic performance of the prototype were evaluated in 36 SPECT studies in 35 patients including bone (n = 21), brain (n = 5), lung perfusion (n = 3), and parathyroid (n = 3) and one study each of sentinel node and labeled white blood cells. Images were graded on a scale of 1–4 for sharpness, contrast, overall quality, and diagnostic confidence. Results: Digital CZT SPECT provided a statistically significant improvement in sharpness and contrast in clinical cases (mean score of 3.79 ± 0.61 vs. 3.26 ± 0.50 and 3.92 ± 0.29 vs. 3.34 ± 0.47 respectively, p < 0.001 for both). Overall image

Journal

EJNMMI PhysicsSpringer Journals

Published: Mar 14, 2018

References

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