gmail.com Department of Nuclear Medicine, Background: The performance of a prototype novel digital single-photon emission Chaim Sheba Medical Center, Tel computed tomography (SPECT) camera with multiple pixelated CZT detectors and Hashomer, Ramat Gan, Israel Sackler School of Medicine, Tel high sensitivity collimators (Digital SPECT; Valiance X12 prototype, Molecular Aviv University, Tel Aviv, Israel Dynamics) was evaluated in various clinical settings. Full list of author information is Images obtained in the prototype system were compared to images from an analog available at the end of the article camera fitted with high-resolution collimators. Clinical feasibility, image quality, and diagnostic performance of the prototype were evaluated in 36 SPECT studies in 35 patients including bone (n = 21), brain (n = 5), lung perfusion (n = 3), and parathyroid (n = 3) and one study each of sentinel node and labeled white blood cells. Images were graded on a scale of 1–4 for sharpness, contrast, overall quality, and diagnostic confidence. Results: Digital CZT SPECT provided a statistically significant improvement in sharpness and contrast in clinical cases (mean score of 3.79 ± 0.61 vs. 3.26 ± 0.50 and 3.92 ± 0.29 vs. 3.34 ± 0.47 respectively, p < 0.001 for both). Overall image
EJNMMI Physics – Springer Journals
Published: Mar 14, 2018
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