Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical results

Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical... gmail.com Department of Nuclear Medicine, Background: The performance of a prototype novel digital single-photon emission Chaim Sheba Medical Center, Tel computed tomography (SPECT) camera with multiple pixelated CZT detectors and Hashomer, Ramat Gan, Israel Sackler School of Medicine, Tel high sensitivity collimators (Digital SPECT; Valiance X12 prototype, Molecular Aviv University, Tel Aviv, Israel Dynamics) was evaluated in various clinical settings. Full list of author information is Images obtained in the prototype system were compared to images from an analog available at the end of the article camera fitted with high-resolution collimators. Clinical feasibility, image quality, and diagnostic performance of the prototype were evaluated in 36 SPECT studies in 35 patients including bone (n = 21), brain (n = 5), lung perfusion (n = 3), and parathyroid (n = 3) and one study each of sentinel node and labeled white blood cells. Images were graded on a scale of 1–4 for sharpness, contrast, overall quality, and diagnostic confidence. Results: Digital CZT SPECT provided a statistically significant improvement in sharpness and contrast in clinical cases (mean score of 3.79 ± 0.61 vs. 3.26 ± 0.50 and 3.92 ± 0.29 vs. 3.34 ± 0.47 respectively, p < 0.001 for both). Overall image http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png EJNMMI Physics Springer Journals

Feasibility study of a novel general purpose CZT-based digital SPECT camera: initial clinical results

Loading next page...
 
/lp/springer_journal/feasibility-study-of-a-novel-general-purpose-czt-based-digital-spect-S3H1ESRndl
Publisher
Springer International Publishing
Copyright
Copyright © 2018 by The Author(s).
Subject
Medicine & Public Health; Nuclear Medicine; Imaging / Radiology; Applied and Technical Physics; Computational Mathematics and Numerical Analysis; Engineering, general
eISSN
2197-7364
D.O.I.
10.1186/s40658-018-0205-z
Publisher site
See Article on Publisher Site

Abstract

gmail.com Department of Nuclear Medicine, Background: The performance of a prototype novel digital single-photon emission Chaim Sheba Medical Center, Tel computed tomography (SPECT) camera with multiple pixelated CZT detectors and Hashomer, Ramat Gan, Israel Sackler School of Medicine, Tel high sensitivity collimators (Digital SPECT; Valiance X12 prototype, Molecular Aviv University, Tel Aviv, Israel Dynamics) was evaluated in various clinical settings. Full list of author information is Images obtained in the prototype system were compared to images from an analog available at the end of the article camera fitted with high-resolution collimators. Clinical feasibility, image quality, and diagnostic performance of the prototype were evaluated in 36 SPECT studies in 35 patients including bone (n = 21), brain (n = 5), lung perfusion (n = 3), and parathyroid (n = 3) and one study each of sentinel node and labeled white blood cells. Images were graded on a scale of 1–4 for sharpness, contrast, overall quality, and diagnostic confidence. Results: Digital CZT SPECT provided a statistically significant improvement in sharpness and contrast in clinical cases (mean score of 3.79 ± 0.61 vs. 3.26 ± 0.50 and 3.92 ± 0.29 vs. 3.34 ± 0.47 respectively, p < 0.001 for both). Overall image

Journal

EJNMMI PhysicsSpringer Journals

Published: Mar 14, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off