Int Urol Nephrol (2017) 49:1585–1591 DOI 10.1007/s11255-017-1637-4 UROLOGY - ORIGINAL PAPER FDG‑PET/CT for response evaluation of invasive bladder cancer following neoadjuvant chemotherapy 1 2 1 3 E. E. Fransen van de Putte · E. Vegt · L. S. Mertens · A. Bruining · 1 4 1 1 K. Hendricksen · M. S. van der Heijden · S. Horenblas · B. W. G. van Rhijn Received: 28 April 2017 / Accepted: 5 June 2017 / Published online: 3 July 2017 © Springer Science+Business Media B.V. 2017 Abstract downstaging (pPR or pCR) was identified with 83% sen - Purpose We investigated the accuracy of FDG-PET/CT sitivity and 80% specificity. Tumor pCR was detected with response identification following neoadjuvant or induction 70% sensitivity and 71% specificity. pCR of overall disease chemotherapy (NAIC) for invasive bladder cancer (BC) as (primary tumor and LNs, n = 17) was detected with 67% to better select patients for radical cystectomy (RC). sensitivity and 75% specificity. CSS was positively associ - Methods Between 2010 and 2014, 37 cT1-4N1-3 BC ated with pathologic CR (HR 0.16, p = 0.027), but not with patients received a FDG-PET/CT before and after NAIC metabolic CR (HR 0.560, p = 0.612). followed
International Urology and Nephrology – Springer Journals
Published: Jul 3, 2017
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