FDA investigation decreases opioid prescribing in children

FDA investigation decreases opioid prescribing in children PharmacoEconomics & Outcomes News 792, p11 - 2 Dec 2017 FDA investigation decreases opioid prescribing in children An investigation by the US FDA into opioid prescribing for children after tonsillectomy and/or adenoidectomy, which lead to a black box warning in February 2013, appears to have achieved a reduction in opioid prescribing for these patients, according to findings of a study published in Pediatrics. Truven MarketScan Commercial Claims and Encounters data were used to investigate prescribing of opioid analgesics (codeine, hydrocodone, oxycodone or others) within 7 days after tonsillectomy and/or adenoidectomy in 362 992 US children with private insurance who underwent this surgery between 2010 and 2015. There was a significant reduction in the proportion of patients who received one or more prescription fills for codeine between 2010 and 2015 (–13.3 percentage points). Overall, 31.0% of patients received one or more prescription fills for codeine in January 2010 compared with 5.1% in December 2015. The FDA investigation was associated with a nonsignificant reduction in the prescribing of opioids other than codeine (–1.2 percentage points). However, other factors lead to an increase in the proportion of children receiving alternative opioids, from 31.7% in January 2010 to 46.1% in December 2015. "Future quality-improvement efforts should focus on eliminating this residual inappropriate codeine prescribing and on encouraging the use of effective nonopioid medications such as ibuprofen," said the authors. Chua KP, et al. Effect of FDA Investigation on Opioid Prescribing to Children After Tonsillectomy/Adenoidectomy. Pediatrics : 16 Nov 2017. Available from: URL: http://doi.org/10.1542/peds.2017-1765 803284957 1173-5503/17/0792-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved PharmacoEconomics & Outcomes News 2 Dec 2017 No. 792 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png PharmacoEconomics & Outcomes News Springer Journals

FDA investigation decreases opioid prescribing in children

Free
1 page
Loading next page...
1 Page
 
/lp/springer_journal/fda-investigation-decreases-opioid-prescribing-in-children-Z3kIF0GofT
Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Pharmacoeconomics and Health Outcomes; Quality of Life Research; Health Economics; Public Health
ISSN
1173-5503
eISSN
1179-2043
D.O.I.
10.1007/s40274-017-4534-2
Publisher site
See Article on Publisher Site

Abstract

PharmacoEconomics & Outcomes News 792, p11 - 2 Dec 2017 FDA investigation decreases opioid prescribing in children An investigation by the US FDA into opioid prescribing for children after tonsillectomy and/or adenoidectomy, which lead to a black box warning in February 2013, appears to have achieved a reduction in opioid prescribing for these patients, according to findings of a study published in Pediatrics. Truven MarketScan Commercial Claims and Encounters data were used to investigate prescribing of opioid analgesics (codeine, hydrocodone, oxycodone or others) within 7 days after tonsillectomy and/or adenoidectomy in 362 992 US children with private insurance who underwent this surgery between 2010 and 2015. There was a significant reduction in the proportion of patients who received one or more prescription fills for codeine between 2010 and 2015 (–13.3 percentage points). Overall, 31.0% of patients received one or more prescription fills for codeine in January 2010 compared with 5.1% in December 2015. The FDA investigation was associated with a nonsignificant reduction in the prescribing of opioids other than codeine (–1.2 percentage points). However, other factors lead to an increase in the proportion of children receiving alternative opioids, from 31.7% in January 2010 to 46.1% in December 2015. "Future quality-improvement efforts should focus on eliminating this residual inappropriate codeine prescribing and on encouraging the use of effective nonopioid medications such as ibuprofen," said the authors. Chua KP, et al. Effect of FDA Investigation on Opioid Prescribing to Children After Tonsillectomy/Adenoidectomy. Pediatrics : 16 Nov 2017. Available from: URL: http://doi.org/10.1542/peds.2017-1765 803284957 1173-5503/17/0792-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved PharmacoEconomics & Outcomes News 2 Dec 2017 No. 792

Journal

PharmacoEconomics & Outcomes NewsSpringer Journals

Published: Dec 2, 2017

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off