Familial Correlations of the Ages of Manifestation of Lung Cancer and Large-Intestine Cancer

Familial Correlations of the Ages of Manifestation of Lung Cancer and Large-Intestine Cancer The probability to develop lung cancer before 80 years of age is 1.67 and 0.18% for the male and female populations of Kharkov, respectively; the probability to develop large-intestine cancer is 0.92 and 0.49%, respectively. The correlation coefficient (r) of the age of manifestation (AM) of cancer in parent–offspring pairs is 0.47. These correlation coefficients for the father–son, mother–daughter, mother–son, and father–daughter pairs are 0.64, 0.49, 0.44, and 0.37, respectively. If the parent has lung cancer, the correlation is stronger (r = 0.71). On average, cancer is manifested in offspring earlier than in parents (57 and 63 years, respectively); the differences in the father–daughter and mother–son pairs are 8.2 and 2.8 years, respectively. The best prognostic parameter is the AM of cancer in the father with respect to the AM in the son (b yx = 0.45). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Familial Correlations of the Ages of Manifestation of Lung Cancer and Large-Intestine Cancer

Loading next page...
Kluwer Academic Publishers-Plenum Publishers
Copyright © 2003 by MAIK “Nauka/Interperiodica”
Biomedicine; Human Genetics
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial